| Project/Area Number |
26670751
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Tohoku University |
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Principal Investigator |
Nakazawa Toru 東北大学, 医学(系)研究科(研究院), 教授 (30361075)
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| Co-Investigator(Kenkyū-buntansha) |
Kunikata HIROSHI 東北大学, 医学系研究科, 准教授 (40361092)
Ida TOMOAKI 東北大学, 医学系研究科, 助教 (70570406)
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| Co-Investigator(Renkei-kenkyūsha) |
Akaike TAKAAKI 東北大学, 医学系研究科, 教授 (20231798)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 抗酸化物質 / 活性イオウ分子種 / 糖尿病網膜症 / 酸化ストレス / メタボローム解析 / 硝子体サンプル / 前房水サンプル |
|---|
| Outline of Final Research Achievements |
We found that there were reactive persulfides and polysulfides in blood, aqueous humor and vitreous in diabetic eyes as well as controls. Furthermore, the concentration of some persulfides was different between diabetic eyes and controls, and there were some correlations between the persulfides in aqueous humor and vitreous.
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