| Project/Area Number |
26670773
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Nagasaki University |
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Principal Investigator |
YANO Hiroki 長崎大学, 病院(医学系), 講師 (60325652)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Katsuya 長崎大学, 病院(医学系), 客員研究員 (70722750)
HIRANO Akiyoshi 長崎大学, 医歯薬学総合研究科(医学系), 教授 (90208835)
樫山 和也 長崎大学, 病院(医学系), 医員 (60723591)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | miRNA / 骨形成 / 骨調整 / G蛋白質 / 顔面骨 |
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| Outline of Final Research Achievements |
This study is primarily intended to control the bone cycle such as bone formation and resorption with siRNAs. Since miR-142 has related to immune system, we’ve gotten the results that it also contributes to the low-weight molecular G proteins operating cytoskeletal action based on the bioinformatics. Although miR-142 signals could not be found in the murine femur by in situ hybridization, miR-142-3p and miR-142-5p were newfound in immune cells by qPCR after cDNA cloning from miRNA extractions.
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