Diagnostic significant of saliva anti-CCP antibody in the RA
| Project/Area Number |
26670821
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
TSUKINOKI Keiichi 神奈川歯科大学, 歯学研究科(研究院), 教授 (00298233)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 唾液検査 / 自己免疫疾患 / 自己抗体 / CCP / 関節リウマチ / 抗CCP抗体 / 唾液腺 |
|---|
| Outline of Final Research Achievements |
The saliva test attracts attention as a substitute of the blood test. It is hoped that I contribute to early detection and the preventive health care of the lesion in particular. The applicants announced usefulness and the problems of the saliva test as an article so far. On the other hand, as for the rheumatoid arthritis, early treatment can control the damages of the joint. In late years, as for the autoimmune disease, early detection becomes an important problem. Specific high anti-CCP antibody was blood concentration-dependent and, in this study, performed detailed inspection about quantify ability whether was secreted in saliva for a diagnosis of the rheumatoid arthritis. As a result, the anti-CCP antibody related to a blood concentration with quantity of saliva. From this, the detection of anti-CCP antibody of saliva may be useful for a diagnosis of the autoimmune disease.
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Report
(3 results)
Research Products
(25 results)
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[Journal Article] Relationship between brain-derived neurotrophic factor and stress in saliva and salivary glands2014
Author(s)
Saruta Juri, To Masahiro, Hayashi Takashi, Kawashima Rie, Shimizu Tomoko, Kamata Yohei, Kato Momoko, Takeuchi Mifumi, Tsukinoki Keiichi
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Journal Title
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Volume: 26
Issue: 3
Pages: 379-389
DOI
Related Report
Peer Reviewed
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[Presentation] Effects of Weekly One-Hour Hatha Yoga Therapy on Resilience and Stress Levels in Patients with Schizophrenia-Spectrum Disorders: A Randomized Controlled Eight-Week Trial2015
Author(s)
Saeko Ikai, Takefumi Suzuki, Juri Saruta, Keiichi Tsukinoki, Ryosuke Kitahata, Hideaki Tani, Nobuhiro Nagai, Aki Endo, Ai Otani, Masaru Mimura, Yasuo Fujii, Hiroyuki Uchida
Organizer
15th International Congress on Schizophrenia Research
Place of Presentation
Colorado Springs, Colorado, USA
Year and Date
2015-03-28 – 2015-04-01
Related Report
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[Presentation] ストレスに対する唾液腺産性物質の効果2015
Author(s)
東雅啓, 猿田樹理, 近藤裕介, 佐藤允俊, 林隆司, 山本裕子, 清水智子, 槻木恵一
Organizer
第146回 神奈川歯科大学例会
Place of Presentation
横須賀, 神奈川
Year and Date
2015-01-08
Related Report
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[Presentation] Relationship of sleep bruxism and migraine2014
Author(s)
Kato Momoko, Saruta Juri, Takeuchi Mifumi, Igarashi Hisaka, Kawata Toshitsugu, Tsukinoki Keiichi
Organizer
4th European Headache and Migraine Trust International Congress
Place of Presentation
Copenhagen, Denmark
Year and Date
2014-09-18 – 2014-09-21
Related Report
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[Presentation] Effect of treatment sprint in migraine patients2014
Author(s)
Takeuchi Mifumi, Saruta Juri, Kato Momoko, Igarashi Hisaka, Kawata Toshitsugu, Tsukinoki Keiichi
Organizer
4th European Headache and Migraine Trust International Congress
Place of Presentation
Copenhagen, Denmark
Year and Date
2014-09-18 – 2014-09-21
Related Report
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