Quantitative evaluation system of dysphagia in Parkinson's disease

• Project/Area Number: 26670833
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Niigata University
• Principal Investigator: Ono Takahiro 新潟大学, 医歯学系, 教授 (30204241)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: パーキンソン病 / 嚥下障害 / 舌 / 舌圧

Outline of Final Research Achievements

Tongue pressure during swallowing was measured using sensor sheet system attached to the hard palate in 30 Parkinson's disease (PD) patients (average age; 69.4 yrs) and 20 healthy control subjects (71.6 yrs) without dysphagia. The maximum magnitude of tongue pressure (MTP) in PD patients was lower than that in healthy subjects. MTP in PD patients with dysphagia was lower than that without dysphagia. MTP on the median part of hard palate was negatively correlated with SDQ-J Score which was subjective measure of dysphagia. Abnormal tongue pressure production patterns which were not seen in healthy subjects were frequently seen in PD patients irrespective with dysphagia. These results suggested that tongue pressure measurement might be useful for the early detection of dysphagia symptom in PD patients.

Research Products

• [Journal Article] 咀嚼・嚥下における舌圧の意味と可能性 (2016)
  • Author(s): 小野高裕，堀 一浩，藤原茂弘，皆木祥伴
  • Journal Title: 日本補綴学会誌 Volume: 8 Pages: 46-51
  • NAID: 130005128717
• [Journal Article] 舌圧検査：新しい評価ツールへの期待 (2015)
  • Author(s): 小野高裕，堀 一浩，藤原茂弘
  • Journal Title: 嚥下医学 Volume: 4 Pages: 178-181
  • Peer Reviewed
• [Presentation] 準備期・口腔期のバイオメカニズム～舌圧研究から見えてくるもの～ (2015)
  • Author(s): 小野高裕
  • Organizer: にいがた摂食嚥下障害サポート研究会
  • Place of Presentation: 新潟大学歯学部（新潟県新潟市）
  • Year and Date: 2015-11-29
  • Invited
• [Presentation] 咀嚼・嚥下における舌圧の意味 (2015)
  • Author(s): 小野高裕
  • Organizer: 第124回日本補綴歯科学会臨床スキルアップセミナー「口腔機能の客観的評価としての舌圧測定：その意義，開発から展望まで」
  • Place of Presentation: 大宮ソニックシティ（埼玉県大宮市）
  • Year and Date: 2015-05-30
  • Invited
• [Presentation] Tongue pressure biomechanics in swallowing. (2015)
  • Author(s): Ono T, Hori K
  • Organizer: Workshop on orofacial motor control for swallow and vocalization.
  • Place of Presentation: 大阪大学（吹田市）
  • Year and Date: 2015-03-25
  • Invited
• [Presentation] Relation between dysphagia and tongue pressure during swallowing in Parkinson’s disease patients (2015)
  • Author(s): Yoshitomo Minagi, Takahiro Ono, Kazuhiro Hori, Shigehiro Fujiwara, Yoshitsugu Tokuda, Kazuhiro Murakami, Makoto Inoue,Yoshinobu Maeda, Saburo Sakoda, Masaru Yokoe, Hideki Mochizuki.
  • Organizer: THE DYSPHAGIA RESEARCH SOCIETY 23st ANNUAL MEETING
  • Place of Presentation: The Westin Michigan Avenue (Chicago, USA)
  • Year and Date: 2015-03-12
• [Presentation] Assessment of Tongue pressure measurement during swallowing in Parkinson's Disease. (2014)
  • Author(s): Yoshitomo Minagi, Takahiro Ono, Kazuhiro Hori, Shigehiro Fujiwara, Yoshitsugu Tokuda, Kazuhiro Murakami, Makoto Inoue,Yoshinobu Maeda, Saburo Sakoda, Masaru Yokoe, Hideki Mochizuki.
  • Organizer: European Society of swallowing Disorders
  • Place of Presentation: Brussels 44 Center (Burussels, Belgium)
  • Year and Date: 2014-10-25
• [Presentation] 舌圧測定によるパーキンソン病患者の嚥下障害の評価 (2014)
  • Author(s): 皆木祥伴、小野高裕、藤原茂弘、徳田佳嗣、村上和裕、前田芳信、三原雅史、小仲邦、横江勝、望月秀樹
  • Organizer: 第8回パーキンソン病・運動障害疾患コングレス
  • Place of Presentation: 京都ホテルオークラ（京都市）
  • Year and Date: 2014-10-04
• [Book] 老年歯科医学 (2015)
  • Author(s): 小野高裕
  • Total Pages: 467
  • Publisher: 医歯薬出版