Elucidation of the oral biofilm prevention mechanism by photocatalytic devices and their practical application

• Project/Area Number: 26670901
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Social dentistry
• Research Institution: University of Tsukuba
• Principal Investigator: YANG Yingnan 筑波大学, 生命環境系, 教授 (50561007)
• Co-Investigator(Renkei-kenkyūsha): KAWAZOE Naoki 国立研究開発法人物質・材料研究機構, 機能性材料研究拠点, 主幹研究員 (90314848)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 光触媒デバイス / バイオフィルム / 口腔衛生 / 反応機構 / Ag/Ag3PO4-TiO2

Outline of Final Research Achievements

In order to prevent the oral biofilm, a developed photocatalytic device used for detect the practical effect and the prevention mechanism also be elucidated.
P/Ag2O/Ag/Ag3PO4/TiO2, a novel photocatalyst developed in our lab was used in this research. In this research, the optimal molecular weight and addition dosage of PEG and calcination temperature, time and number of coating layers was investigated to optimize the coating condition of PEGm-P/Ag/Ag2O/Ag3PO4/TiO2 photocatalytic thin film. The result of E.coli (107CFU/ml) inactivation by using PEG modified photocatalyst showed that all of the E.coli was destroyed by P/Ag/Ag2O/Ag3PO4/TiO2 only in 10 minutes, but pure TiO2 have little effect on sterilization. Furthermore, the oral biofilm prevention effect have been demonstrated and the mechanism also be elucidated. The valuable information for future practical application have been obtained.

Research Products

• [Journal Article] Influence of cell size on cellular uptake of gold nanoparticles (2016)
  • Author(s): Wang, X., Hu, X., Li, J., Adriana C. Mulero Russe, Kawazoe, N., Yang, Y. N. Chen, G
  • Journal Title: Biomaterial Science Volume: 4 Pages: 970-978
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Manipulating cell nanomechanics using micropatterned surfaces (2016)
  • Author(s): Wang, X., Hu, X., Kawazoe, N., Yang, Y. N. Chen, G.
  • Journal Title: Advanced Functional Materials Volume: 26 Pages: 7634-7643
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Morphological and mechanical properties of osteosarcoma microenvironment cells explored by atomic force microscopy (2016)
  • Author(s): 8.Wang, X., Yang, Y. J., Hu, X., Kawazoe, N., Yang, Y. N. Chen, G.
  • Journal Title: Analytical Sciences Volume: 32 Pages: 1177-1182
  • NAID: 130005278005
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] An alternative anaerobic treatment process for treatment of heavy oil refinery wastewater containing polar organics. (2016)
  • Author(s): Wang, Y., Wang, Q., Li, M., Yang, Y. N., He, W., Yan, G., Guo, S.
  • Journal Title: Biochemical Engineering Journal Volume: 105 Pages: 44-51
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Ultrasonic-Assisted Extraction and Antioxidant Activities of the Polysaccharides Extracted from Soybean Curd Residue Fermented by Flammulina velutipes. (2016)
  • Author(s): Ma J., Sun, H., Yang, Y. N., Zhang, Z. Y.
  • Journal Title: International Journal of Biology. Volume: 8 Pages: 1-8
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of anti-hyperglycemic effect of Actinidia koomikta (Maxim. et Rur.) Maxim. root extract. (2015)
  • Author(s): Hu, X. S, Cheng, D., Wang, L., Li, S., Wang, Y., Li, K., Yang, Y. N., Zhang, Z. Y.
  • Journal Title: Pak. J. Pharm. Sci. Volume: 28 Pages: 1135-1140
  • Peer Reviewed
• [Journal Article] Bioactivity evaluation of crude polysaccharide from rice bran fermented by Preussia aemulans and the changes in its nutritional contents (2015)
  • Author(s): Li, Y., Meng, S., Wang, L., Shi, M., Hu, X. S, Yang, Y. N., Zhang, Z. Y.
  • Journal Title: Journal of Food Biochemistry Volume: 40 Pages: 67-75
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Degradation of microcystin-LR by highly efficient AgBr/Ag3PO4/TiO2 heterojunction photocatalyst under simulated solar light irradiation (2015)
  • Author(s): Wang, X., Utsumi, M., Yang, Y. N., Li, D. W., Zhao, Y., Zhang, Z., Feng, C., Sugiura, N., Cheng, J. J.
  • Journal Title: Applied Surface Sciences. Volume: 325 Pages: 1-12
  • Peer Reviewed
• [Journal Article] Photocatalytic degradation of recalcitrant organic pollutants in water using a novel cylindrical multi-column photoreactor packed with TiO2-coated silica gel beads. (2015)
  • Author(s): Li, D. W., Zhu, Q., Han, C., Yang, Y. N., Jinag, W. Z., Zhang, Z. Y.
  • Journal Title: Journal of Hazardous Materials Volume: 285 Pages: 398-408
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Photocatalytic removal of Microcystin-LR by advanced WO3-based nanoparticles under simulated solar light. (2015)
  • Author(s): Zhao, C., Liu, Y. G., Feng, C. P., Zhang, Z. Y., Sugiura, N., Yang, Y. N
  • Journal Title: The Scientific World Journal Volume: 2015 Issue: 1 Pages: 1-9
  • DOI: 10.1155/2015/720706
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Degradation of Rhodamine B by Highly Efficient Photocatalyst TiO2-Ag/Ag+ under Simulated Sunlight Irradiation (2014)
  • Author(s): Yang, Y. N., Zhu, Q., Li, D. W., Hu, X. H.
  • Journal Title: Advanced Materials Research Volume: 1051 Pages: 112-116
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Improving anaerobic methane production from ammonium-rich piggery waste in a zeolite-fixed bioreactor and evaluation of ammonium adsorbed on zeolite A-3 as fertilizer (2014)
  • Author(s): Yu, C., Li, D. W., Wang, Q. H., Zhang, Z. Y.,Yang, Y. N
  • Journal Title: International Journal of Waste Resources Volume: 160 Issue: 04 Pages: 1-8
  • DOI: 10.4172/2252-5211.1000160
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A novel double-cylindrical-shell photoreactor immobilized with monolayer TiO2-coated silica gel beads for photocatalytic degradation of Rhodamine B and Methyl Orange in aqueous solution (2014)
  • Author(s): Li, D., Zheng, H., Wang, Q., Wang, X., Jiang, W., Zhang, Z. Y., Yang, Y. N.
  • Journal Title: Separation and Purification Technology Volume: 123 (26) Pages: 130-138
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] 太陽光を利用した活性汚泥の可溶化促進及び光メタン発酵システムの開発 (2014)
  • Author(s): 楊 英男
  • Journal Title: 再生と利用 Volume: 39(144) Pages: 82-86
  • NAID: 40020179314
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] Development of Highly Efficient Visibal-light-driven P/Ag/Ag2O/Ag3PO4/TiO2 Photocatalyst (2017)
  • Author(s): Yang, Y. N.
  • Organizer: Shanghai University International Cooperation Symposium
  • Place of Presentation: Shanghai University, Shanghai, China
  • Year and Date: 2017-03-16
  • Int'l Joint Research / Invited
• [Presentation] Enhanced bactericidal activity of Escherichia coli with a novel TiO2 based composite synthesized by a hydrothermal method (2017)
  • Author(s): Liu, N., Zhu, Q., Negishi, N., Yang, Y. N.
  • Organizer: つくば医工連携フォーラム2017
  • Place of Presentation: 国立法人物質材料研究機構千現地区、茨城県つくば
  • Year and Date: 2017-01-20
• [Presentation] Preparation of Ag-Based Bi2WO6 Thin Film with Enhanced Photocatalytic Activity for Degradation of Wastewater (2017)
  • Author(s): Ma, Q. S., Hu, X. H., Yang, Y. N.
  • Organizer: つくば医工連携フォーラム2017
  • Place of Presentation: 国立法人物質材料研究機構千現地区、茨城県つくば
  • Year and Date: 2017-01-20
• [Presentation] Comparing the Water Splitting Efficiency of Photocatalytic Composite Prepared Under Different Calcination Temperature by Hydrothermal Method (2017)
  • Author(s): Nagai, D., Zhu, Q., Yang, Y. N.
  • Organizer: つくば医工連携フォーラム2017
  • Place of Presentation: 国立法人物質材料研究機構千現地区、茨城県つくば
  • Year and Date: 2017-01-20
• [Presentation] Physico-chemical Properties of Visible Light-responsive TiO2-based Nanophotocatalyst with Silver Dopant and Improved Photocatalytic Ability by Hydrothermal Method. (2017)
  • Author(s): Zhu, Q., Hu, X. H., Stanislaus, M.S., Yang, Y. N
  • Organizer: つくば医工連携フォーラム2017
  • Place of Presentation: 国立法人物質材料研究機構千現地区、茨城県つくば
  • Year and Date: 2017-01-20
• [Presentation] Photodynamic therapy for cancer cells by TiO2 based nano photosensertizer (2017)
  • Author(s): Hu, X. H., Wang X. L., Zhu, Q., Zhang, N., Kawazoe N., Yang, Y. N.
  • Organizer: つくば医工連携フォーラム2017
  • Place of Presentation: 国立法人物質材料研究機構千現地区、茨城県つくば
  • Year and Date: 2017-01-20
• [Presentation] 可視光利用型新規光触媒材料の研究開発 (2016)
  • Author(s): 楊 英男
  • Organizer: 第14回環境研究シンポジウム
  • Place of Presentation: 一橋大学、東京都、千代田区
  • Year and Date: 2016-11-22
• [Presentation] Development of Highly Efficient Visibal-light-driven TiO2 Photocatalyst (2016)
  • Author(s): Yang, Y. N., Hu, X. H., Zhang, N., Stanislaus, M.S.
  • Organizer: The 12th IUPAC International Conference on Novel Materials and their Synthesis (NMS-XII)
  • Place of Presentation: Changsha, China
  • Year and Date: 2016-10-14
  • Int'l Joint Research / Invited
• [Presentation] Improvement of silver modified TiO2 solar-light-driven photocatalyst by hydrothermal method (2016)
  • Author(s): Zhu, Q., Hu, X. H., Mishma, S. S., Yang, Y. N.
  • Organizer: 68th SBJ Annual Meeting
  • Place of Presentation: Toyama International Conference Center,ANA Crowne Plaza Toyama, Toyama, Toyama-city
  • Year and Date: 2016-09-28
• [Presentation] Inactivation of Escherichia coli using P/Ag/Ag2O/Ag3PO4/TiO2 photocatalyst under LED irradiation (2016)
  • Author(s): Liu, N., Zhu, Q., Xiao, R. D., Yang, Y. N.
  • Organizer: 68th SBJ Annual Meeting
  • Place of Presentation: Toyama International Conference Center,ANA Crowne Plaza Toyama, Toyama, Toyama-city
  • Year and Date: 2016-09-28
• [Presentation] Development of P/Ag/Ag2O/Ag3PO4/TiO2 thin film modified by polyethylene glycol for water treatment (2016)
  • Author(s): Ma, Q. S., Dong, Z. T., Zhu, Q., Hu, X. H., Yang, Y. N.
  • Organizer: 68th SBJ Annual Meeting
  • Place of Presentation: Toyama International Conference Center,ANA Crowne Plaza Toyama, Toyama, Toyama-city
  • Year and Date: 2016-09-28
• [Presentation] Effect of Hydrothermal Treatment on Physico-chemical Properties of Visible Light-responsive P/Ag/Ag2O/Ag3PO4/TiO2 Photocatalyst (2016)
  • Author(s): Zhu, Q., Hu, X. H., Stanislaus, M.S., Yang, Y. N.
  • Organizer: The 9th Korea-China-Japan Graduate Student Forum
  • Place of Presentation: Chungnam National University,Daejeon, Korea
  • Year and Date: 2016-09-20
  • Int'l Joint Research
• [Presentation] Effects of experiment conditions on the inactivation of Escherichia coli using P/Ag/Ag2O/Ag3PO4/TiO2 photocatalyst under LED irradiation. (2016)
  • Author(s): Liu, N., Zhu, Q., Negishi, N., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2016
  • Place of Presentation: University of Tsukuba, Tsukuba, Ibaraki, Japan
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] Enhancement of P/Ag/Ag2O/Ag3PO4/TiO2 Solar-light-driven Photocatalyst by Hydrothermal Method (2016)
  • Author(s): Zhu, Q., Hu, X. H., Stanislaus, M.S., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2016
  • Place of Presentation: University of Tsukuba,Tsukuba, Ibaraki, Japan
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] Synthesization of PEG Modified P/Ag/Ag2O/Ag3PO4/TiO2 Photocatalyst (2016)
  • Author(s): Dong, Z. T., Zhu, Q., Hu, X. H., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2016
  • Place of Presentation: University of Tsukuba,Tsukuba, Ibaraki, Japan
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] Optimization of H2 and O2 Generation in Water-splitting Process by P/Ag/Ag2O/Ag3PO4/TiO2 photocatalyst under Solar Light (2016)
  • Author(s): Hu, X. H., Shen, H. X., Zhu, Q., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2016
  • Place of Presentation: University of Tsukuba,Tsukuba, Ibaraki, Japan
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] Preparation of Ag-based Bi2WO6 Thin Film on Glass Substrate with Enhanced Photocatalytic Activity for Decomposition of Organic Dye (2016)
  • Author(s): Ma, Q. S., Hu, X. H., Zhu, Q., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2016
  • Place of Presentation: University of Tsukuba,Tsukuba, Ibaraki, Japan
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] Comparing the Water Splitting Efficiency by Using Different Temperature of Hydrothermal Synthesis of Photocatalytic Composite Under Solar Light (2016)
  • Author(s): Nagai, D., Zhu, Q., Shen, H. X., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2016
  • Place of Presentation: University of Tsukuba, Tsukuba, Ibaraki, Japan
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] Preparation, Characterization and Application of a Novel TiO2 Based Photosensitizer for Photodynamic Therapy (2015)
  • Author(s): Hu, X. H., Zhu, Q., Xiao, R. D., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2015
  • Place of Presentation: University of Tsukuba, Tsukuba, Japan
  • Year and Date: 2015-11-16
  • Int'l Joint Research
• [Presentation] Evaluation of Microorganism Inactivation in Water Environments by using P/Ag/Ag2O/Ag3PO4/TiO2 Thin Film Reactor Circle System under LED Irradiation (2015)
  • Author(s): Xiao, R. D., Hu, X. H., Zhu, Q., Yang, Y. N.
  • Organizer: Ag-ESD Symposium 2015
  • Place of Presentation: University of Tsukuba, Tsukuba, Japan
  • Year and Date: 2015-11-16
  • Int'l Joint Research
• [Presentation] Enhanced photocatalytic disinfection of E.coli using P/Ag/Ag2O/Ag3PO4/TiO2 photocatalytic reactor under LED irradiation. (2015)
  • Author(s): Xiao, R. D., Zhu, Q., Hu, X. H., Yang, Y. N.
  • Organizer: 67th SBJ Annual Meeting
  • Place of Presentation: 城山観光ホテル、鹿児島県、鹿児島市
  • Year and Date: 2015-10-26
• [Presentation] Preparation of a novel TiO2 based photosensitizer and its application for photodynamic therapy. (2015)
  • Author(s): Hu, X. H., Zhu, Q., Wang, X. L., Kawazoe, N., Yang, Y. N.
  • Organizer: 67th SBJ Annual Meeting
  • Place of Presentation: 城山観光ホテル、鹿児島県、鹿児島
  • Year and Date: 2015-10-26
• [Presentation] Efficient photocatalytic ability of novel P/Ag/Ag2O/Ag3PO4/TiO2 thin film on glass substrate for decomposition of recalcitrant organic waste under simulated solar light (2015)
  • Author(s): Zhu, Q., Hu, X. H., Li, D. W., Yang, Y. N.
  • Organizer: The 8th Japan-China-Korea Graduate Student Forum
  • Place of Presentation: University of Tsukuba,Tsukuba, Japan
  • Year and Date: 2015-09-16
  • Int'l Joint Research
• [Presentation] Development of a novel TiO2 based photosensitizer for photodynamic therapy (2015)
  • Author(s): Hu, X. H., Zhu, Q., Xiao, R., Yang, Y. N.
  • Organizer: The 8th Japan-China-Korea Graduate Student Forum
  • Place of Presentation: University of Tsukuba, Tsukuba, Japan
  • Year and Date: 2015-09-16
  • Int'l Joint Research
• [Presentation] Photocatalytic Cytotoxic effect of Ag/Ag3PO4-TiO2 Particles to Hela Cells (2015)
  • Author(s): Yang, Y. N., Hu, X. H., Wang, X. L., Kawazoe, N.
  • Organizer: The 5th Asian Biomaterials Congress (ABMC5 2015)
  • Place of Presentation: Chientan Youth Activity Center, Taipei, Taiwan
  • Year and Date: 2015-05-06 – 2015-05-09
• [Presentation] Promotional Photocatalytic Activity of Novel Ag/Ag3PO4/TiO2 Thin Film on Glass Substrate for Decomposition of Recalcitrant Organic Waste under Solar Light (2015)
  • Author(s): Zhu, Q., Li, D.W., Hu, X., H. Yang, Y. N.
  • Organizer: 49th JSWE Annual Meeting
  • Place of Presentation: Kanazawa University, Japan
  • Year and Date: 2015-03-16 – 2015-03-18
• [Presentation] Preparation and Characterization of Highly Efficient Visible-Light-Driven Ag/Ag3PO4-TiO2Photocatalyst for Degradation of Rhodamine B Solution (2015)
  • Author(s): Hu, X. H., Zhu, Q., Kawazoe, N., Yang, Y. N.
  • Organizer: 49th JSWE Annual Meeting
  • Place of Presentation: Kanazawa University, Japan
  • Year and Date: 2015-03-16 – 2015-03-18
• [Presentation] Synthesization of Ni-TiO2Nanocomposite Photocatalyst by Sol-gel Coating for Rhodamine B Degradation underVisible Light Irradiation (2015)
  • Author(s): 6.Song, Y. Y., Gu, Z. B., Zhu, Q., Li, D.W., , Hu, X. H., Yang, Y. N.
  • Organizer: 49th JSWE Annual Meeting
  • Place of Presentation: Kanazawa University, Japan
  • Year and Date: 2015-03-16 – 2015-03-18
• [Presentation] Enhanced Photocatalytic Disinfection of E.coli using Ag/Ag3PO4/TiO2Photocatalytic Reactor under LED Irradiation (2015)
  • Author(s): Xiao, R. D., Zhu, Q., Hu, X. H., Yang, Y. N.
  • Organizer: 49th JSWE Annual Meeting, March 16-18
  • Place of Presentation: Kanazawa University, Japan
  • Year and Date: 2015-03-16 – 2015-03-18
• [Presentation] Application of Refractory Wastewater Treatment by Developing PEGm-TiO2 Coated Glass Beads Technology (2015)
  • Author(s): Gu, Z. B., Zhu, Q., Li, D.W., Hu, X. H., Yang, Y. N.
  • Organizer: 49th JSWE Annual Meeting
  • Place of Presentation: Kanazawa University, Japan
  • Year and Date: 2015-03-16 – 2015-03-18
• [Presentation] 光触媒を用いた水中病原性微生物の不活化評価 (2015)
  • Author(s): 田中 絵里，楊 英男, 張 振亜
  • Organizer: 第49回日本水環境学会年会
  • Place of Presentation: 金沢大学
  • Year and Date: 2015-03-16 – 2015-03-18
• [Presentation] Enhancement of Photocatalysis and Ultrasonication Synergy for Treating Refractory Organic Wastewater by Using PEGm-TiO2 Coated Glass Beads (2014)
  • Author(s): Gu, Z. B., Li, D. W., Hu, X. H., Zhu, Q., Yang, Y. N.
  • Organizer: International Symposium on Agriculture Education for Sustainable Development
  • Place of Presentation: University of Tsukuba, Japan
  • Year and Date: 2014-11-10 – 2014-11-14
• [Presentation] Synthesization of Ni/TiO2 Nanocomposite Photocatalyst for Water Purification under Solar Light (2014)
  • Author(s): Song, Y. Y, Li, D. W., Zhu, Q., Hu, X. H., Yang, Y. N.
  • Organizer: International Symposium on Agriculture Education for Sustainable Development
  • Place of Presentation: University of Tsukuba, Japan
  • Year and Date: 2014-11-10 – 2014-11-14
• [Presentation] Novel Ag/Ag3PO4/TiO2 Thin Film on Glass Substrate for Efficient Decomposition of Recalcitrant Organic Waste under Solar Light (2014)
  • Author(s): Zhu, Q., Hu, X. H., Li, D. W., Yang, Y. N.
  • Organizer: International Symposium on Agriculture Education for Sustainable Development
  • Place of Presentation: University of Tsukuba, Japan
  • Year and Date: 2014-11-10 – 2014-11-14
• [Presentation] Photocatalytic Disinfection of E. coli in Surface Water by Ag/Ag3PO4/TiO2 Coated on the Substrate under LED Irradiation. (2014)
  • Author(s): Xiao, R. D., Hu, X. H., Zhu, Q., Yang, Y. N.
  • Organizer: nternational Symposium on Agriculture Education for Sustainable Development
  • Place of Presentation: University of Tsukuba, Japan
  • Year and Date: 2014-11-10 – 2014-11-14
• [Presentation] Characterization of Visible-Light-Driven Ag/Ag3PO4-TiO2 Photocatalyst. (2014)
  • Author(s): Hu, X. H., Zhu, Q., Yang, Y. N.
  • Organizer: International Symposium on Agriculture Education for Sustainable Development, Tsukuba
  • Place of Presentation: University of Tsukuba, Japan
  • Year and Date: 2014-11-10 – 2014-11-14
• [Presentation] Degradation of Rhodamine B by Highly Efficient Photocatalyst TiO2-Ag/Ag+ under Simulated Sunlight Irradiation. (2014)
  • Author(s): Yang, Y. N.*, Zhu, Q., Li, D. W., Hu, X. H.
  • Organizer: 2014 International Conference on Green Materials and Environmental Engineering
  • Place of Presentation: Hong Kong, China
  • Year and Date: 2014-09-21 – 2014-09-22
• [Patent(Industrial Property Rights)] 可視光で利用できる光触媒 (2016)
  • Inventor(s): 楊英男、呼小紅
  • Industrial Property Rights Holder: 楊英男、呼小紅
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2016-218918
  • Filing Date: 2016-11-09
• [Patent(Industrial Property Rights)] 光触媒、塗膜および殺菌デバイス (2014)
  • Inventor(s): 楊 英男
  • Industrial Property Rights Holder: 楊 英男
  • Industrial Property Rights Type: 特許
  • Filing Date: 2014-09-18