| Project/Area Number |
26670904
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
Morita Manabu 岡山大学, 医歯薬学総合研究科, 教授 (40157904)
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| Co-Investigator(Kenkyū-buntansha) |
丸山 貴之 岡山大学, 大学病院, 助教 (30580253)
江國 大輔 岡山大学, 大学病院, 講師 (70346443)
友藤 孝明 岡山大学, 医歯薬学総合研究科, 准教授 (80335629)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 膵臓がん / 生命予後 / 歯周病 / 腫瘍マーカー / 酸化ストレス |
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| Outline of Final Research Achievements |
Patients diagnosed with pancreatobiliary tract cancer were analyzed. Factors affecting the prognosis of pancreatobiliary tract cancer were evaluated. The results demonstrated that low body mass index, high concentration of serum C-reactive protein (CRP) and severe periodontitis were significant prognostic factors for survival rate. It was also found that micro-RNAs in salivary exosomes could be candidate biomarkers for pancreatobiliary tract cancer.
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