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Utility of the M-test for oxaliplatin-induced peripheral neuropathy

Research Project

Project/Area Number 26670958
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Clinical nursing
Research InstitutionUniversity of Miyazaki

Principal Investigator

Oku Shoko  宮崎大学, 医学部, 教授 (40284921)

Co-Investigator(Kenkyū-buntansha) 緒方 昭子  森ノ宮医療大学, 保健医療学部, 准教授 (50510731)
矢野 朋実  宮崎大学, 医学部, 講師 (90363580)
Co-Investigator(Renkei-kenkyūsha) Shimoda kazuya  宮崎大学, 医学部, 教授 (90311844)
Research Collaborator Mukaino Yoshito  
Kubota Yuko  
Yonemaru Junko  
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsオキサリプラチン / 末梢神経障害 / 大腸がん / M-Test / 主観的症状 / 補完・代替医療
Outline of Final Research Achievements

We investigated the utility of the motion-induced somatic response test (M-test))in patients with peripheral neuropathy induced by oxaliplatin administered in the treatment of colorectal cancer. We evaluated subjective symptoms using questions set with reference to the Functional Assessment of Cancer Therapy (FACT; for neurotoxicity) version 4.0 and previous studies, and evaluated objective signs using thermography and the Japanese translation (JCOG version) of the Common Terminology Criteria for Adverse Events (CTCAE) version 4.0.Compared with NRS scores before M-Test, scores on the day after treatment were unchanged in four participants and had changed in eight participants. Before starting treatment, 15 participants reported a sensation of numbness and tingling pain in the hands or feet.Symptom diary: Participants wrote that numbness appeared to be alleviated slightly faster, that they developed an appetite. No noticeable changes were seen in blood test data,thermography and CTCAE

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (1 results)

All 2016

All Presentation (1 results)

  • [Presentation] オキサリプラチンによる末梢神経障害へのM-Testの試み2016

    • Author(s)
      奥祥子、矢野朋実、緒方昭子
    • Organizer
      第30回日本がん看護学会学術集会
    • Place of Presentation
      千葉幕張
    • Year and Date
      2016-02-21
    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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