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Analysis of cerebral prefrontal cortex activation via cranial nerve stimulation and development into cognitive function rehabilitation

Research Project

Project/Area Number 26671027
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Gerontological nursing
Research InstitutionFukuoka College of Health Sciences

Principal Investigator

Okura Yoshifumi  福岡医療短期大学, 保健福祉学科, 教授 (80352293)

Co-Investigator(Kenkyū-buntansha) 力丸 哲也  福岡医療短期大学, 歯科衛生学科, 教授 (10299589)
Co-Investigator(Renkei-kenkyūsha) YAMAKAWA Takeshi  一般財団法人ファジィシステム研究所, 研究部, 所長 (00005547)
AOU Shuji  九州工業大学, 生命体工学研究科(研究院), 教授 (40150908)
HORIO Keiichi  九州工業大学, 生命体工学研究科(研究院), 教授 (70363413)
Research Collaborator IMAMURAYA Ritsuko  福岡大学, スポーツ科学部, 准教授 (90289554)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords認知機能 / 学習効率 / 大脳前頭前野 / 脳内変化 / 近赤外線分光法
Outline of Final Research Achievements

Dementia including Alzheimer's disease is a pathological condition that seriously deteriorates the quality of life (QOL) of the elderly persons. In this research, using measurement technique of the Near Infrared Spectroscopy (NIRS) that can visualize the changes in the cerebral prefrontal cortex activity related to cognitive and learning functions, we found that learning efficiency of Stroop test, that is one of the evaluation test for execution function and selective attention function, has been improved by the cranial nerve stimulation, such as intra-oral cold stimulation via the trigeminal nerve (cranial nerve V) or mint-related olfactory and/or taste stimulus via the facial nerve (cranial nerve I and VII), accompanied by the activation of the prefrontal cortex area. Furthermore, we have proceeded with the investigation on the improvement of cognitive function in the elderly persons, following incorporation of the cranial nerve stimulation tasks into the oral care program.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2018 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] Trigeminal nerve-related cold stimuli activate the cerebral prefrontal cortex regions related to cognitive performance2018

    • Author(s)
      Tetsuya Rikimaru, Yoshifumi Okura
    • Journal Title

      Journal of Fukuoka Dental College

      Volume: 43

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Evaluation of the Effect of Tooth Brushing on Prefrontal Cortex Activity in Young Adult Subjects2015

    • Author(s)
      力丸 哲也, 大倉 義文, 栢 豪洋
    • Journal Title

      Ronen Shika Igaku

      Volume: 29 Issue: 4 Pages: 329-339

    • DOI

      10.11259/jsg.29.329

    • NAID

      130005065029

    • ISSN
      0914-3866, 1884-7323
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] The evaluation of the effect of intra-oral menthol stimulus on the activity of prefrontal cortex in young adult subjects.(ミント系刺激による大脳前頭前野活性化についての検討)2015

    • Author(s)
      大倉義文、力丸哲也、粟生修司、栢豪洋、山川烈
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-07-29
    • Related Report
      2015 Research-status Report
  • [Presentation] Brain-Science-Based Training System for Autistic Disorder2014

    • Author(s)
      山川 烈, 今村律子, 大倉義文
    • Organizer
      第 27 回バイオメディカル・ファジィ・システム学会年次大会
    • Place of Presentation
      昭和大学
    • Year and Date
      2014-11-15 – 2014-11-16
    • Related Report
      2014 Research-status Report
  • [Presentation] For Exercise Program Construction in Facility that Supports the Disabled2014

    • Author(s)
      今村律子, 山川 烈, 大倉義文, 力丸哲也
    • Organizer
      第 27 回バイオメディカル・ファジィ・システム学会年次大会
    • Place of Presentation
      昭和大学
    • Year and Date
      2014-11-15 – 2014-11-16
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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