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Immunological assessment of participatory intervention for workplace improvements among university hospital nurses

Research Project

Project/Area Number 26671048
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Community health nursing
Research InstitutionInternational University of Health and Welfare (2017)
University of Occupational and Environmental Health, Japan (2014-2016)

Principal Investigator

NAKATA Akinori  国際医療福祉大学, 医学研究科, 教授 (80333384)

Co-Investigator(Renkei-kenkyūsha) ANAN Ayumi  産業医科大学, 産業保健学部, 教授 (00369076)
OTSUKA Yasumasa  筑波大学, 人間系, 准教授 (90350371)
KODAMA Hiromi  産業医科大学, 産業保健学部, 助教 (80584515)
Research Collaborator TONDOKORO Tsukumi  
YANAGIHARA Nobuyuki  
KAWASAKI Mikiko  
SATOH Noriaki  
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords看護師 / 職場環境改善 / 介入研究 / 生理指標 / 免疫指標 / サイトカイン / 自律神経バランス / 参加型 / 自律神経 / 職業性ストレス / 過重労働
Outline of Final Research Achievements

The purpose of this study was to evaluate the effects of participatory workplace improvement program on biological indices among the university hospital nurses. A total of 36 female nurses decided to improve work conditions such as 1) leave work on time (no overtime), 2) give thanks card to co-workers, and 3) take actions in advance for caring patients. The program lasted for 3 months and the evaluation was measured before (time 0), right after the program (time 1), and 3 months after finishing the program (time 2). We found a significant decrease of cytokines (TNF-α,IL-12/23p40, and IL-15) at time 2 compared to time 0 but no other indicators, such as perceived job stress or autonomic balance, was significantly improved. No significant differences were observed in job stress or autonomic indicators between time 0 and 1. Although the results need to be interpreted cautiously, the findings suggest a delayed response of intervention effect.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (52 results)

All 2018 2017 2016 2015 2014

All Journal Article (15 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 14 results,  Open Access: 5 results,  Acknowledgement Compliant: 3 results) Presentation (30 results) (of which Int'l Joint Research: 5 results,  Invited: 7 results) Book (7 results)

  • [Journal Article] Stressors and the Sense of Coherence Related to the Mental Health of Nurses Assuming the Roles of Wives and/or Mothers — Investigation into the Effects of Leaving Jobs Because of Marriage, Childbirth, and Childrearing2018

    • Author(s)
      岡田 なぎさ, 中田 光紀, 中野 正博, 酒井 久美子, 鷹居 樹八子, 児玉 裕美, 小林 敏生
    • Journal Title

      Journal of UOEH

      Volume: 40 Issue: 1 Pages: 53-63

    • DOI

      10.7888/juoeh.40.53

    • NAID

      130006515873

    • ISSN
      0387-821X, 2187-2864
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Pilot Study of Healthy Living Options at 16 Truck Stops Across the United States.2017

    • Author(s)
      Lincoln JE, Birdsey J, Sieber WK, Chen GX, Hitchcock EM, Nakata A, Robinson CF.
    • Journal Title

      Am J Health Promot

      Volume: in press Issue: 3 Pages: 546-53

    • DOI

      10.1177/0890117116670289

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Long working hours, job satisfaction, and depressive symptoms: a community-based cross-sectional study among Japanese employees in small- and medium-scale businesses.2017

    • Author(s)
      Nakata A.
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 32 Pages: 53041-52

    • DOI

      10.18632/oncotarget.18084

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Occupational safety and health aspects of corporate social responsibility reporting in Japan from 2004 to 2012.2017

    • Author(s)
      Nagata T, Nakata A, Mori K, Maruyama T, Kawashita F, Nagata M.
    • Journal Title

      BMC Public Health

      Volume: 17 Issue: 1 Pages: 381-381

    • DOI

      10.1186/s12889-017-4356-y

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Work to live, to die, or to be happy?2017

    • Author(s)
      Nakata A.
    • Journal Title

      Industrial Health

      Volume: 55 Issue: 2 Pages: 93-94

    • DOI

      10.2486/indhealth.55-93

    • NAID

      130005558258

    • ISSN
      0019-8366, 1880-8026
    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Open Access
  • [Journal Article] 職業性ストレスの免疫学的指標―細胞性免疫とサイトカインを中心にー2017

    • Author(s)
      中田光紀
    • Journal Title

      産業ストレス研究

      Volume: 24 Pages: 197-204

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 職業性ストレスの免疫学的指標-細胞性免疫とサイトカインを中心に2017

    • Author(s)
      中田光紀
    • Journal Title

      産業ストレス研究

      Volume: 24 Pages: 197-204

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association of Suicidal Ideation with Job Demands and Job Resources: a Large Cross-Sectional Study of Japanese Workers2016

    • Author(s)
      Otsuka, Y., Nakata, A., Sakurai, K., & Kawahito, J.
    • Journal Title

      International journal of behavioral medicine

      Volume: なし Issue: 4 Pages: 1-9

    • DOI

      10.1007/s12529-016-9534-2

    • Related Report
      2017 Annual Research Report 2016 Research-status Report 2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Interrelationships between job resources, vigor, exercise habit, and serum lipids in Japanese employees: a multiple group path analysis using medical checkup data2016

    • Author(s)
      Watanabe K, Otsuka Y, Inoue A, Sakurai K, Ui A, Nakata A.
    • Journal Title

      Int J Behav Med

      Volume: 23 Issue: 4 Pages: 410-417

    • DOI

      10.1007/s12529-015-9516-9

    • Related Report
      2017 Annual Research Report 2016 Research-status Report 2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Workplace psychosocial and organizational factors for neck pain in workers in the United States.2016

    • Author(s)
      Yang H, Hitchcock E, Haldeman S, Swanson N, Lu ML, Choi B, Nakata A, Baker D.
    • Journal Title

      Am J Ind Med

      Volume: 59(7) Issue: 7 Pages: 549-560

    • DOI

      10.1002/ajim.22602

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Number of Patients Examined May Affect Natural Killer Cell Activity in Japanese Emergency Physicians:2016

    • Author(s)
      Okamoto H, Teruya K, Nakata A, Yamaguchi Y, Matsuda T, Tsunoda T.
    • Journal Title

      Japanese Journal of Health and Human Ecology

      Volume: 82 Issue: 2 Pages: 73-82

    • DOI

      10.3861/jshhe.82.73

    • NAID

      130005147446

    • ISSN
      0368-9395, 1882-868X
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Work engagement and high-sensitivity C-reactive protein levels among Japanese workers: A 1-year prospective cohort study2015

    • Author(s)
      Eguchi H, Shimazu A, Kawakami N, Inoue A, Nakata A, Tsutsumi A
    • Journal Title

      International Archives of Occupational and Environmental Health

      Volume: 印刷中 Issue: 6 Pages: 651-658

    • DOI

      10.1007/s00420-014-0995-9

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Source-specific social support and circulating inflammatory markers among white-collar employees2014

    • Author(s)
      Akinori Nakata, Masahiro Irie, Masaya Takahasahi
    • Journal Title

      Annals of Behavioral Medicine

      Volume: 47 Issue: 3 Pages: 335-346

    • DOI

      10.1007/s12160-013-9555-x

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] A 2-year prospective cohort study of white-collar employees2014

    • Author(s)
      Akinori Nakata, Masahiro Irie, Masaya Takahasahi
    • Journal Title

      International Journal of Psychophysiology

      Volume: 94 Pages: 233-233

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The association of interpersonal conflict at the workplace and immunity: A cross-sectional study among white-collar enployees at a trading company2014

    • Author(s)
      Nozomi Sonoda, Akinori Nakata, Masahiro Irie, Masaya Takahasahi
    • Journal Title

      International Journal of Psychophysiology

      Volume: 94 Pages: 232-233

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 幸福感・肯定感情、睡眠と健康2017

    • Author(s)
      中田光紀
    • Organizer
      第23回日本行動医学会学術総会
    • Place of Presentation
      沖縄科学技術大学院大学(沖縄県国頭郡恩納村)
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 働く人々における喫煙・受動喫煙 と労働災害との関連2017

    • Author(s)
      中田光紀,大和浩
    • Organizer
      第26回日本禁煙推進医師歯科医師連盟学術会議
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2017-02-12
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 労働者の喫煙・受動喫煙と主観的健康感との関連2017

    • Author(s)
      山田妙子,中田光紀,大和浩
    • Organizer
      第26回日本禁煙推進医師歯科医師連盟学術会議
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2017-02-12
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 喫煙行動の変容に伴う生理学的指標の変化:1年間の追跡研究より2017

    • Author(s)
      中田光紀,永田智久,塩田直樹,大和浩.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 労働者における睡眠・生活の不規則性と自殺念慮の関連:労働者10万人を対象とした大規模疫学調査2017

    • Author(s)
      中田光紀,大塚泰正,永田智久.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 職業性ストレスと自覚的体重増加の関連2017

    • Author(s)
      石橋理恵,頓所つく実,中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 日本における幸福感に関する研究の動向2017

    • Author(s)
      井上由貴子. 中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 冠危険因子と免疫・ストレスの関連性に関する文献レビュー2017

    • Author(s)
      緒方友登. 中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 爪試料コルチゾールを用いた職業性ストレス評価の文献的考察2017

    • Author(s)
      川崎幹子, 中田光紀, 井澤修平.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ポリオ罹患患者の精神的QOLと身体機能,生活満足感との関連2017

    • Author(s)
      木村公宣, 中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 働く人々における睡眠とワーク・エンゲージメントの関連2017

    • Author(s)
      田中朝美,秋吉葉月,中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 働く人々の頭痛の有症率―性別,年齢,業種別解析―2017

    • Author(s)
      頓所つく実. 中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 残業時間と多様な睡眠の動態との関連2017

    • Author(s)
      花田佑季,藤本朱音,中田光紀.
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Influence of Occupational Stress on Autonomic Nervous Balance: Development of Software for Automatic Assay System and its Evaluation2017

    • Author(s)
      柳原延章, 豊平由美子, 佐藤教昭, 中田光紀, 中尾智, 浅海洋,
    • Organizer
      第35回産業医科大学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 労働者における喫煙・受動喫煙と自殺企図の関連2017

    • Author(s)
      中田光紀.
    • Organizer
      第90回日本産業衛生学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 働く人々における睡眠と頭痛の関連2017

    • Author(s)
      頓所つく実 中田光紀.
    • Organizer
      第90回日本産業衛生学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 労働者コホートを利用した精神神経免疫学的研究:研究1年後の成果2017

    • Author(s)
      中田光紀,井澤修平
    • Organizer
      第23回精神神経内分泌免疫学研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 労働者コホートを利用した精神神経免疫学的研究:研究開始1年後の成果2017

    • Author(s)
      中田光紀,井澤修平
    • Organizer
      第23回精神神経内分泌免疫学研究会
    • Place of Presentation
      東海学園大学名古屋キャンパス(愛知県名古屋市)
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Overtime and immunity: A 2-year prospective study among healthy daytime white-collar employees.2016

    • Author(s)
      Nakata A, Irie M, Takahashi M
    • Organizer
      The 14th International Congress of Behavioral Medicine
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2016-12-06
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Job stress and the immune system2016

    • Author(s)
      Nakata A.
    • Organizer
      6th Expert workshop on psychosocial factors at work in the Asia Pacific
    • Place of Presentation
      Fudan University, Shanghai, China
    • Year and Date
      2016-10-20
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Self-rated health and circulating cytokines: Comparisons between four different health measures and the impact of age among healthy male individuals2016

    • Author(s)
      Nakata A, Nagata T, Otsuka Y.
    • Organizer
      18th World Congress of Psychophysiology
    • Place of Presentation
      Melia Habana Hotel, Havana, Cuba
    • Year and Date
      2016-08-31
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Optimism and inflammatory markers: A preliminary study in a healthy working population2016

    • Author(s)
      Nakata A, Nagata T, Otsuka Y.
    • Organizer
      18th World Congress of Psychophysiology
    • Place of Presentation
      Melia Habana Hotel, Havana, Cuba
    • Year and Date
      2016-08-31
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 妻/母親役割を持つ看護師の精神健康度への関連要因 -ライフイベントによる離職経験の有無別の検討-2016

    • Author(s)
      岡田なぎさ,中田光紀,中野正博,小野久美子,鷹居樹八子,児玉裕美,富岡明子,小林敏生
    • Organizer
      日本看護研究学会第42回学術集会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2016-08-20
    • Related Report
      2016 Research-status Report
  • [Presentation] Literature review on QOL assessment of parents with children suffering from disorders2016

    • Author(s)
      Hirowatari K, Hamada Y, Matsuura T, Fujita A, Nakata A, Kaku T.
    • Organizer
      19th East Asian Forum of Nursing Scholars
    • Place of Presentation
      幕張メッセ(千葉県・千葉市)
    • Year and Date
      2016-03-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 職業性ストレスと血圧の関連 ―ストレスチェック項目を用いた疫学研究―2016

    • Author(s)
      津留寿江里,重廣亜佑美,伊藤美月,有吉明香里,中田光紀
    • Organizer
      第34回産業医科大学学会
    • Place of Presentation
      産業医科大学(福岡県北九州市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 社会的支援と血圧の関連について -健診データを用いた疫学研究-2016

    • Author(s)
      伊藤美月,有吉明香里,津留寿江里,重廣亜佑美,中田光紀
    • Organizer
      第34回産業医科大学学会
    • Place of Presentation
      産業医科大学(福岡県北九州市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 受動喫煙とメンタルヘルスとの関連性に関する文献レビュー2016

    • Author(s)
      山田妙子,中田光紀,大和浩
    • Organizer
      第34回産業医科大学学会
    • Place of Presentation
      産業医科大学(福岡県北九州市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 睡眠など仕事外の要因からみた健康いきいき2016

    • Author(s)
      中田光紀
    • Organizer
      東京都「職場のメンタルヘルス対策推進キャンペーン」協力セミナー
    • Place of Presentation
      公益財団法人日本生産性本部(東京都渋谷区)
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 労働者コホートを利用した 精神神経免疫学的研究:研究計画の紹介2016

    • Author(s)
      中田光紀
    • Organizer
      第22回精神神経内分泌免疫学研究会
    • Place of Presentation
      九州大学応用生理人類学研究センター(福岡県福岡市)
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Long working hours, job satisfaction, and depression among full-time employees of small- and medium-scale businesses2014

    • Author(s)
      Akinori Nakata
    • Organizer
      International Commision on Occupational Health: Work Organization and Psychosocial Factors 2014 Congress
    • Place of Presentation
      Adelaide Convention Center, Adelaide, Australia
    • Year and Date
      2014-09-17 – 2014-09-19
    • Related Report
      2014 Research-status Report
  • [Book] 「働く女性のストレスとメンタルヘルスケア(丸山総一郎編)」2017

    • Author(s)
      中田光紀
    • Total Pages
      381
    • Publisher
      創元社
    • ISBN
      4422116282
    • Related Report
      2017 Annual Research Report
  • [Book] 「商品開発・評価のための整理計測とデータ解析ノウハウ」2017

    • Author(s)
      中田光紀
    • Total Pages
      298
    • Publisher
      NTS出版
    • ISBN
      4860434633
    • Related Report
      2017 Annual Research Report
  • [Book] 産業保健心理学(島津明人編)2017

    • Author(s)
      中田光紀
    • Total Pages
      255
    • Publisher
      ナカニシヤ出版
    • ISBN
      4779512069
    • Related Report
      2017 Annual Research Report
  • [Book] 海外における女性労働者のメンタルヘルス対策:先進諸国の取り組み. In: 丸山総一郎(編)働く女性のストレスとメンタルヘルスケア.2017

    • Author(s)
      中田光紀
    • Total Pages
      381
    • Publisher
      創元社
    • Related Report
      2016 Research-status Report
  • [Book] 職業性ストレス理論モデルの開発と健康影響. In: 島津明人(編著)産業保健心理学.2017

    • Author(s)
      中田光紀
    • Publisher
      ナカニシヤ出版
    • Related Report
      2016 Research-status Report
  • [Book] 商品開発・評価のための生理計測と データ解析ノウハウー免疫指標2017

    • Author(s)
      中田光紀
    • Total Pages
      298
    • Publisher
      NTS出版
    • Related Report
      2016 Research-status Report
  • [Book] 睡眠マネジメント―産業衛生・疾病との係わりから最新改善対策まで2014

    • Author(s)
      中田光紀
    • Total Pages
      354
    • Publisher
      株式会社エヌ・ティー・エス
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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