Non-contact Single Cell Manipulation by High Speed On-chip Microrobot
| Project/Area Number |
26709014
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Kyushu Institute of Technology |
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Principal Investigator |
Kawahara Tomohiro 九州工業大学, 大学院生命体工学研究科, 准教授 (20575162)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Fiscal Year 2016: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
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| Keywords | マイクロロボット / 流体制御 / マイクロ流体チップ |
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| Outline of Final Research Achievements |
In this research, we have developed a non-contact manipulation method by using fluid field generated by on-chip microrobot for fine positioning of single particle and living cell. The newly developed experimental platform with a high-speed actuator and a high-speed camera was used to investigate the basic characteristics of the generated fluid field. As a result, we found that it is highly required to compensate the disturbance of fluid flow for improving the positioning accuracy of single target during the manipulation. By adjusting the control parameter (amplitude and frequency) of the microrobot in real time, we succeeded in 10 um order positioning of single microparticle by non-contact actuation. Finally, the developed manipulation technique was applied to stimulate a single swimming-microorganism under the stable environment of closed microchip. The unique dynamic behavior of Paramecium was observed after the local point stimulation.
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Report
(4 results)
Research Products
(13 results)
