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High sensitive 3D micro coil for MRI imaging of a cell

Research Project

Project/Area Number 26709015
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionChuo University

Principal Investigator

Dohi Tetsuji  中央大学, 理工学部, 准教授 (20447436)

Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥23,660,000 (Direct Cost: ¥18,200,000、Indirect Cost: ¥5,460,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
KeywordsMEMS・NEMS / マイクロコイル / 核磁気共鳴画像(MRI) / マイクロ・ナノメカトロニクス / マイクロセンサー / マイクロマシン / MRI
Outline of Final Research Achievements

In this study, we fabricated high sensitive micro RF coils for small samples and high efficiency micro gradient coils for small magnetic resonance imaging (MRI) apparatus. As a high sensitive micro RF coil, screw shaped micro coils, bicone-shaped micro coils, and spring shaped micro coils were fabricated. By assembling flexible Cu/polyimide substrate onto 3D printed jigs, we fabricated gradient micro coils for a compact MRI system. Since the gradient magnetic field efficiency was 10 times stronger than the hand-winding coils, high resolution MRI image can be expected.
Then the micro RF coils, the gradient micro coils, and an alignment mechanism were integrated as a compact MRI system. As a result, MRI images with voxel size of 50 μm were realized, and we could take MRI images of small samples such as a Xenopus oocyte.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (26 results)

All 2018 2017 2016 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (24 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results)

  • [Journal Article] A Low-resistance and Low-parasitic Capacitance Micro Coil for MRI Fabricated by Selective Deposition on 3D Stepped Helical Structures2017

    • Author(s)
      Tetsuji Dohi, Yuya Yokoyama
    • Journal Title

      IEEJ Transactions on Sensors and Micromachines

      Volume: 137 Issue: 1 Pages: 2-7

    • DOI

      10.1541/ieejsmas.137.2

    • NAID

      130005188435

    • ISSN
      1341-8939, 1347-5525
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Micro Saddle Coil with Switchable Sensitivity for Local High-Resolution Imaging of Luminal Tissue2016

    • Author(s)
      Tetsuji Dohi, Kousuke Murashige
    • Journal Title

      Micromachines

      Volume: 7(4) Issue: 4 Pages: 67-67

    • DOI

      10.3390/mi7040067

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] A compact magnetic resonance imaging system integrated micro RF and gradient coils for small sample measurement2018

    • Author(s)
      Dai Tsuchiya, Tetsuji Dohi
    • Organizer
      The 31th International Conference on Micro Electro Mechanical Systems
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 段差円筒形状を利用した低寄生容量なMRI用マイクコイル2018

    • Author(s)
      工藤耕太,土肥徹次
    • Organizer
      電気学会バイオマイクロシステム研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] キャパシタ分割により自己共振周波数を向上したMRI用マイクロコイル2017

    • Author(s)
      土屋大,土肥徹次
    • Organizer
      第56回日本生体医工学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 小型MRIのための勾配磁場マイクロコイル2017

    • Author(s)
      土屋大,土肥徹次
    • Organizer
      第21回NMRマイクロイメージング研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 小型MRIのための3次元冶具を用いた勾配磁場マイクロコイル2017

    • Author(s)
      土屋大,土肥徹次
    • Organizer
      第8回マイクロナノ工学シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] ばね形状への真空蒸着による低抵抗なMRI用マイクロコイル2017

    • Author(s)
      曾俊皓・田中恒士郎・土肥徹次
    • Organizer
      第8回マイクロナノ工学シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 微小試料のMRI画像計測のための勾配磁場マイクロコイル2017

    • Author(s)
      泉崎友彦,土屋大,土肥徹次
    • Organizer
      日本生体医工学会関東支部 若手研究者発表会2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] Low-resistance RF Micro Coil Fabricated by Selective Deposition on 3D Printed Spring-shaped Structure2017

    • Author(s)
      Chun-Hao Tseng, Koshiro Tanaka, Tetsuji Dohi
    • Organizer
      International conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS & Applications 2017"
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] キャパシタ分割を用いた高感度なMRI用マイクロコイル2016

    • Author(s)
      土屋大,深堀俊,土肥 徹次
    • Organizer
      第33回「センサ・マイクロマシンと応用システム」シンポジウム
    • Place of Presentation
      平戸文化センター,長崎
    • Year and Date
      2016-10-24
    • Related Report
      2016 Annual Research Report
  • [Presentation] 3次元治具を用いた折り畳み多層マイクロコイル2016

    • Author(s)
      深堀俊,土肥徹次
    • Organizer
      フィジカルセンサ バイオ・マイクロシステム合同研究会
    • Place of Presentation
      機械振興会館,東京
    • Year and Date
      2016-08-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] ねじ型二重構造への真空蒸着によるMRIマイクロコイル2016

    • Author(s)
      土肥徹次,関口茜理
    • Organizer
      フィジカルセンサ バイオ・マイクロシステム合同研究会
    • Place of Presentation
      機械振興会館,東京
    • Year and Date
      2016-08-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 低ノイズなMRI画像計測のための二重巻きマイクロコイル2016

    • Author(s)
      深堀俊,土肥徹次
    • Organizer
      ロボティクス・メカトロニクス講演会2016 in Yokohama
    • Place of Presentation
      パシフィコ横浜,横浜
    • Year and Date
      2016-06-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] 微小組織観察のためのマイクロコイルを利用したMRI画像計測2016

    • Author(s)
      土肥徹次
    • Organizer
      平成28年電気学会全国大会
    • Place of Presentation
      東北大学 川内北キャンパス,仙台
    • Year and Date
      2016-03-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] A low resistance and low parasitic capacitance micro coil for MRI fabricated by selective deposition on 3d printed stepped helical structures2016

    • Author(s)
      Yuya Yokoyama, Tetsuji Dohi
    • Organizer
      The 29th IEEE International Conference on Micro Electro Mechanical Systems
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2016-01-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] MRI 画像計測のための真空蒸着を用いた双円錐型マイクロコイル2015

    • Author(s)
      横山 裕也,土肥 徹次
    • Organizer
      第7回マイクロ・ナノ工学シンポジウム
    • Place of Presentation
      朱鷺メッセ,新潟
    • Year and Date
      2015-10-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] フレキシブル基板の 3 次元冶具への固定による MRI 用勾配磁場マイクロコイル2015

    • Author(s)
      岩永 麗樹,土肥 徹次
    • Organizer
      第7回マイクロ・ナノ工学シンポジウム
    • Place of Presentation
      朱鷺メッセ,新潟
    • Year and Date
      2015-10-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] マイクロイメージングのための MEMS 勾配磁場・RFコイル2015

    • Author(s)
      土肥徹次
    • Organizer
      第19回NMRマイクロイメージング研究会
    • Place of Presentation
      慶應義塾大学 日吉キャンパス,横浜
    • Year and Date
      2015-08-12
    • Related Report
      2015 Annual Research Report
  • [Presentation] A bicone-shaped micro coil for high sensitive magnetic resonance imaging of a small sample2015

    • Author(s)
      Yuya Yokoyama, Tetsuji Dohi
    • Organizer
      2015 JSME-IIP/ASME-ISPS Joint Conference on Micromechatronics for Information and Precision Equipment
    • Place of Presentation
      Kobe International Conference Center, Kobe, Japan
    • Year and Date
      2015-06-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] MRI画像計測のためのねじ形状への真空蒸着によるマイクロコイル2015

    • Author(s)
      土肥徹次, 伊藤翼
    • Organizer
      電気学会 バイオ・マイクロシステム研究会
    • Place of Presentation
      中央大学,東京
    • Year and Date
      2015-05-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] 高分解能MRIのための平面型勾配磁場コイル2015

    • Author(s)
      土肥徹次, 杉田慎悟
    • Organizer
      電気学会 バイオ・マイクロシステム研究会
    • Place of Presentation
      中央大学 理工学部,東京
    • Year and Date
      2015-05-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] The Micro Saddle Coil with Switchable Sensitivity for Magnetic Resonance Imaging2015

    • Author(s)
      Kosuke Murashige, Tetsuji Dohi
    • Organizer
      The 28th International Conference on Micro Electro Mechanical Systems
    • Place of Presentation
      Estoril,Portugal
    • Year and Date
      2015-01-18 – 2015-01-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] ねじ形状への真空蒸着による高分解能MRI用マイクロコイル2014

    • Author(s)
      伊藤翼,土肥徹次
    • Organizer
      日本生体医工学会関東支部若手研究者発表会2014
    • Place of Presentation
      東京電機大学,東京
    • Year and Date
      2014-11-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] MRI画像計測のための双円錐型立体マイクロコイル2014

    • Author(s)
      横山裕也,土肥徹次
    • Organizer
      第6回マイクロナノ工学シンポジウム
    • Place of Presentation
      くにびきメッセ,島根
    • Year and Date
      2014-10-20 – 2014-10-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 双円錐型構造により寄生容量を低減したMRI用マイクロコイル2014

    • Author(s)
      横山裕也,土肥徹次
    • Organizer
      ロボティクス・メカトロニクス講演会2014 in 富山
    • Place of Presentation
      富山国際会議場,富山
    • Year and Date
      2014-05-26 – 2014-05-28
    • Related Report
      2014 Annual Research Report

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Published: 2014-04-04   Modified: 2019-03-29  

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