Creation of implants to influence human body using bioresorbable amorphous calcium phosphate films
Project/Area Number |
26709049
|
Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Partial Multi-year Fund |
Research Field |
Composite materials/Surface and interface engineering
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Research Institution | Tohoku University |
Principal Investigator |
Ueda Kyosuke 東北大学, 工学(系)研究科(研究院), 准教授 (40507901)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
Fiscal Year 2016: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2015: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2014: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
|
Keywords | 生体材料 / 材料加工・処理 / 非晶質リン酸カルシウム / コーティング / 抗菌性 / 硬組織適合性 / 骨形成タンパク質 / 薬剤徐放 / リン酸カルシウム |
Outline of Final Research Achievements |
Amorphous calcium phosphate (ACP) film known as bioresorbable material was focused on the surface modification of bone substitutes to improve the bone compatibility. Controlling the bioresorbability and giving the antibacterial activity to the ACP film were conducted by addition of elements and Ag, respectively. Nb and Ta addition to ACP film suppressed the bioresorbability of ACP film. Ag added ACP film showed antibacterial activity against E. coli and S. aureus.
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Report
(4 results)
Research Products
(64 results)