| Budget Amount *help |
¥24,180,000 (Direct Cost: ¥18,600,000、Indirect Cost: ¥5,580,000)
Fiscal Year 2017: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Outline of Final Research Achievements |
The organization of genes in the genome changes during the course of evolution, but the arrangement of a small number (~ 3%) of genes is widely conserved among bilateral animals. It is known that this conserved gene organization (microsynteny) contains many developmental genes (genes expressed at the embryonic developmental stage). In the chordate ascidian, I comprehensively analyzed the genes that constitute microsynteny. In most cases, it was revealed that one of the genes constituting microsynteny was expressed at the embryonic development stage and the other was not expressed at the embryonic development stage. In addition, each genes in the microsynteny has promoters with different properties to prevent gene regulatory regions from interfering with each other.
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