Characterization of flavonoid transport system and its application for the production of useful compoundsb
Project/Area Number |
26712013
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Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Partial Multi-year Fund |
Research Field |
Applied biochemistry
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Research Institution | Kyoto University |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2016: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2015: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2014: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
|
Keywords | フラボノイド / 輸送体 / 有用物質生産 / プラスチド |
Outline of Final Research Achievements |
Plants produce more than 200,000 secondary metabolites, among which flavonoids are a group of over 7,000 compounds. These compounds are important for our lives as pharmaceutical raw materials and functional foods. However, useful secondary metabolites derived from these plants have a large limitation to stable supply because of low contents in plants, origin from rare plant, difficulty in purification. In this study, we aimed to construct stable flavonoid production system using transformants by clarifying transporters of flavonoids.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] Molecular assessment of the bacterial community associated with Cassava (Manihot esculenta Crantz) cultivation in Cameroon2017
Author(s)
Sarr, P.S., Sugiyama, A., Begoudeb, A.D.B, Yazaki, K.,, Araki, S., Nawata, W.
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Journal Title
Microbiological Research
Volume: 197
Pages: 22-28
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Developmental and nutritional regulation of isoflavone secretion from soybean roots2016
Author(s)
Sugiyama, A., Yamazaki, Y., Yamashita, K., Takahashi, S., Nakayama, T., Yazaki, K.
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Journal Title
Bioscience, Biotechnology, and Biochemistry
Volume: 80
Issue: 1
Pages: 89-94
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Molecular characterization of LjABCG1, an ATP-binding cassette protein in Lotus japonicus.2015
Author(s)
Sugiyama, A., Fukuda, S., Takanashi, K., Yoshioka, M., Yoshioka, H., Narusaka, Y., Narusaka, M., Kojima, M., Sakakibara, H., Shitan, N., Sato, S., Tabata, S., Kawaguchi, M. and Yazaki, K.
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Journal Title
PLoS ONE
Volume: 10
Issue: 9
Pages: e0139127-e0139127
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Metabolic engineering of flavonoids with prenyltransferase and chalcone isomerase genes in tomato fruits2014
Author(s)
Kawasaki, K., Koeduka, T., Sugiyama, A., Sasaki, K., Linley, PJ., Shitan, S., Kumano, T., Yamamoto, H., Ezura, H., Kuzuyama, T., Yazaki, K.
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Journal Title
Plant Biotechnology
Volume: 31
Issue: 5
Pages: 567-571
DOI
NAID
ISSN
1342-4580, 1347-6114
Related Report
Peer Reviewed / Acknowledgement Compliant
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