| Budget Amount *help |
¥23,660,000 (Direct Cost: ¥18,200,000、Indirect Cost: ¥5,460,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2015: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
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| Outline of Final Research Achievements |
Innate immune system senses microbial components by pattern-recognition receptors and induces inflammation to eliminate invading microbes. However, innate immune system also senses nutrient-derived stimulatory factors and often causes development of inflammatory diseases. We have conducted studies of inflammation induced by innate immune system, and have revealed mechanisms of development of inflammatory diseases. Furthermore, we have identified chemical compounds capable of inhibiting inflammation induced by innate immune system and have revealed mechanisms of action of anti-inflammatory compounds.
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