Understanding and chemical control of inflammation induced by innate immune system

• Project/Area Number: 26713005
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Biological pharmacy
• Research Institution: The University of Tokushima (2015-2017); Osaka University (2014)
• Principal Investigator: SAITOH Tatsuya 徳島大学, 先端酵素学研究所(次世代), 教授 (60456936)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥23,660,000 (Direct Cost: ¥18,200,000、Indirect Cost: ¥5,460,000); Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2016: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000); Fiscal Year 2015: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000); Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
• Keywords: 炎症 / 自然免疫 / 生活習慣病 / 生体防御 / 薬学 / 抗炎症薬 / オルガネラ / 免疫学 / サイトカイン

Outline of Final Research Achievements

Innate immune system senses microbial components by pattern-recognition receptors and induces inflammation to eliminate invading microbes. However, innate immune system also senses nutrient-derived stimulatory factors and often causes development of inflammatory diseases. We have conducted studies of inflammation induced by innate immune system, and have revealed mechanisms of development of inflammatory diseases. Furthermore, we have identified chemical compounds capable of inhibiting inflammation induced by innate immune system and have revealed mechanisms of action of anti-inflammatory compounds.

Research Products

• [Int'l Joint Research] Yale University School of Medicine(米国)
• [Int'l Joint Research] Washington University School of Medicine/Broad Institute of MIT and Harvard/Harvard Medical School(米国)
• [Journal Article] Autophagy limits activation of the inflammasomes (2018)
  • Author(s): Takahama Michihiro、Akira Shizuo、Saitoh Tatsuya
  • Journal Title: Immunological Reviews Volume: 281 Issue: 1 Pages: 62-73
  • DOI: 10.1111/imr.12613
  • Peer Reviewed
• [Journal Article] Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis. (2017)
  • Author(s): Yamaguchi J, Suzuki C, Nanao T, Kakuta S, Ozawa K, Tanida I, Saitoh T, Sunabori T, Komatsu M, Tanaka K, Aoki S, Sakimura K, Uchiyama Y.
  • Journal Title: Autophagy Volume: 17 Issue: 5 Pages: 1-14
  • DOI: 10.1080/15548627.2017.1314897
  • NAID: 120006881392
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense (2017)
  • Author(s): Sasai Miwa、Sakaguchi Naoya、Ma Ji Su、Nakamura Shuhei、Kawabata Tsuyoshi、Bando Hironori、Lee Youngae、Saitoh Tatsuya、Akira Shizuo、Iwasaki Akiko、Standley Daron M、Yoshimori Tamotsu、Yamamoto Masahiro
  • Journal Title: Nature Immunology Volume: 18 Issue: 8 Pages: 899-910
  • DOI: 10.1038/ni.3767
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses (2017)
  • Author(s): Takahama Michihiro、Fukuda Mitsunori、Ohbayashi Norihiko、Kozaki Tatsuya、Misawa Takuma、Okamoto Toru、Matsuura Yoshiharu、Akira Shizuo、Saitoh Tatsuya
  • Journal Title: Cell Reports Volume: 20 Issue: 12 Pages: 2944-2954
  • DOI: 10.1016/j.celrep.2017.08.085
  • NAID: 120007134819
  • Peer Reviewed / Open Access
• [Journal Article] 痛風関節炎の発症機序 (2017)
  • Author(s): 齊藤達哉
  • Journal Title: カレントテラピー Volume: 35 Pages: 61-65
• [Journal Article] 尿酸塩結晶によるインフラマソーム活性化と痛風性関節炎 (2017)
  • Author(s): 齊藤達哉
  • Journal Title: 尿酸と血糖 Volume: 3 Pages: 6-9
• [Journal Article] 医学用語解説 インフラマソーム (2017)
  • Author(s): 髙濵充寛，齊藤達哉
  • Journal Title: 炎症と免疫 Volume: 25 Pages: 94-96
• [Journal Article] オートファジーと生体防御応答 (2017)
  • Author(s): 渋谷周作, 齊藤達哉, 吉森保
  • Journal Title: 実験医学 Volume: 35 Pages: 144-150
• [Journal Article] 基礎医学―免疫学の最初の一歩 オートファジー (2017)
  • Author(s): 髙濵充寛，齊藤達哉
  • Journal Title: 周産期医学 Volume: 47 Pages: 1513-1519
• [Journal Article] Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis. (2017)
  • Author(s): Yamaguchi J, Suzuki C, Nanao T, Kakuta S, Ozawa K, Tanida I, Saitoh T, Sunabori T, Komatsu M, Tanaka K, Aoki S, Sakimura K, Uchiyama Y
  • Journal Title: Autophagy Volume: 印刷中
  • NAID: 120006881392
  • Peer Reviewed
• [Journal Article] Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. (2017)
  • Author(s): Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T
  • Journal Title: Proc Natl Acad Sci U S A Volume: 114 Issue: 10 Pages: 2681-2686
  • DOI: 10.1073/pnas.1621508114
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Regulation of inflammasomes by autophagy. (2016)
  • Author(s): Saitoh T, Akira S
  • Journal Title: J Allergy Clin Immunol Volume: 138 Issue: 1 Pages: 28-36
  • DOI: 10.1016/j.jaci.2016.05.009
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse. (2016)
  • Author(s): Imagawa Y, Saitoh T, Tsujimoto Y
  • Journal Title: Nat Commun Volume: 7 Issue: 1 Pages: 13391-13391
  • DOI: 10.1038/ncomms13391
  • NAID: 120006535064
  • Peer Reviewed / Open Access
• [Journal Article] Bone-protective Functions of Netrin 1 Protein (2016)
  • Author(s): Kenta Maruyama, Takahiko Kawasaki, Masahide Hamaguchi, Motomu Hashimoto, Moritoshi Furu, Hiromu Ito, Takao Fujii, Naoki Takemura, Thangaraj Karuppuchamy, Takeshi Kondo, Takumi Kawasaki, Masahiro Fukusaka, Takuma Misawa, Tatsuya Saitoh, Yutaka Suzuki, Mikael M Martino, Yutaro Kumagai, and Shizuo Akira
  • Journal Title: Journal of Biological Chemistry Volume: 291 Issue: 46 Pages: 23854-23868
  • DOI: 10.1074/jbc.m116.738518
  • Peer Reviewed
• [Journal Article] Impaired Autophagy in Macrophages Promotes Inflammatory Eye Disease. (2016)
  • Author(s): Santeford A, Wiley LA, Park S, Bamba S, Nakamura R, Gdoura A, Ferguson TA, Rao PK, Guan JL, Saitoh T, Akira S, Xavier R, Virgin HW, Apte RS
  • Journal Title: Autophagy Volume: 12 Issue: 10 Pages: 1876-1885
  • DOI: 10.1080/15548627.2016.1207857
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] オートファジーによる炎症制御 (2016)
  • Author(s): 齊藤達哉
  • Journal Title: 最新医学 Volume: 71 Pages: 16-22
• [Journal Article] 細胞死を介した抗ウイルス応答 (2016)
  • Author(s): 齊藤達哉
  • Journal Title: 実験医学 Volume: 34 Pages: 124-128
• [Journal Article] Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation. (2016)
  • Author(s): Park S, Buck MD, Desai C, Zhang X, Loginicheva E, Martinez J, Freeman ML, Saitoh T, Akira S, Guan JL, He YW, Blackman MA, Handley SA, Levine B, Green DR, Reese TA, Artyomov MN, Virgin HW
  • Journal Title: Cell Host Microbe Volume: 19 Issue: 1 Pages: 91-101
  • DOI: 10.1016/j.chom.2015.12.010
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2016)
  • Author(s): Klionsky DJ., Abdelmohsen K., Abe A., Abedin MJ.,Inomata M., et al.
  • Journal Title: Autophagy Volume: 12(1) Issue: 1 Pages: 1-222
  • DOI: 10.1080/15548627.2015.1100356
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Hyperuricemia-induced inflammasome and kidney diseases. (2015)
  • Author(s): Isaka Y, Takabatake Y, Takahashi A, Saitoh T, Yoshimori T.
  • Journal Title: Nephrol. Dial. Transplant. Volume: - Issue: 6 Pages: 890-896
  • DOI: 10.1093/ndt/gfv024
  • Peer Reviewed
• [Journal Article] p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen. (2015)
  • Author(s): Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, Yamamoto M
  • Journal Title: Cell Rep Volume: 13 Issue: 2 Pages: 223-233
  • DOI: 10.1016/j.celrep.2015.09.005
  • NAID: 120007001422
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of the Atg9a gene in intrauterine growth and survival of fetal mice. (2015)
  • Author(s): Kojima T, Yamada T, Akaishi R, Furuta I, Saitoh T, Nakabayashi K, Nakayama KI, Nakayama K, Akira S, Minakami H
  • Journal Title: Reprod.Biol. Volume: 15 Issue: 3 Pages: 131-138
  • DOI: 10.1016/j.repbio.2015.05.001
  • NAID: 120005828503
  • Peer Reviewed / Open Access
• [Journal Article] Autophagy and autophagy-related proteins in the immune system. (2015)
  • Author(s): Shibutani ST, Saitoh T, Nowag H, Munz C, Yoshimori T
  • Journal Title: Nat Immunoｌ Volume: 16 Issue: 10 Pages: 1014-1024
  • DOI: 10.1038/ni.3273
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Resveratrol inhibits the acetylated a-tubulin-mediated assembly of NLRP3-inflammasome. (2015)
  • Author(s): Misawa T*, Saitoh T*, Kozaki T, Park S, Lee H, Takahama M, Akira S (*Co-first authors).
  • Journal Title: Int Immunol Volume: in press
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Role of zinc-finger antiviral protein in host defense against Sindbis virus. (2015)
  • Author(s): Kozaki T, Takahama M, Misawa T, Matsuura Y, Akira S, Saitoh T* (*Corresponding author).
  • Journal Title: Int Immunol Volume: in press
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] 5-azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival. (2015)
  • Author(s): Maruyama K, Fukasaka M, Uematsu S, Takeuchi O, Kondo T, Saitoh T, Martino M, Akira S.
  • Journal Title: J Biol Chem Volume: 290 Issue: 15 Pages: 9377-9386
  • DOI: 10.1074/jbc.m114.631374
  • Peer Reviewed / Open Access
• [Journal Article] The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy. (2014)
  • Author(s): Choi J, Park S, Biering SB, Selleck E, Liu CY, Zhang X, Fujita N, Saitoh T, Akira S, Yoshimori T, Sibley LD, Hwang S, Virgin HW.
  • Journal Title: Immunity. Volume: 40 Issue: 6 Pages: 924-35
  • DOI: 10.1016/j.immuni.2014.05.006
  • Peer Reviewed
• [Journal Article] Role of Mouse and Human Autophagy Proteins in IFN-γ-Induced Cell-Autonomous Responses against Thxoplasma gondii (2014)
  • Author(s): Jun Ohshima, Youngae Lee, Miwa Sasai, Tatsuya Saitoh, Ji Su Ma, Naganori Kamiyama, Yoshiharu Matsuura, Suh Pann-Ghill, Mikako Hayashi, Shigeyuki Ebisu, Kiyoshi Takeda, Shizuo Akira, and Masahiro Yamamoto.
  • Journal Title: The Journal of Immunology Volume: 192(7) Issue: 7 Pages: 3328-35
  • DOI: 10.4049/jimmunol.1302822
  • Peer Reviewed / Open Access
• [Presentation] 細胞外微粒子による炎症応答の誘導機序解明と制御法開発 (2018)
  • Author(s): 齊藤達哉
  • Organizer: 生化学若い研究者の会「冬のセミナー」
  • Invited
• [Presentation] 細胞外微粒子による炎症応答の誘導機序解明と制御法開発 (2018)
  • Author(s): 齊藤達哉
  • Organizer: 第51回日本痛風・核酸代謝学会総会
  • Invited
• [Presentation] 生体防御応答にかかわるオルガネラ・ゾーンの理解と制御 (2018)
  • Author(s): 齊藤達哉
  • Organizer: 日本薬学会第138年会
  • Invited
• [Presentation] オルガネラ損傷により誘導される自然免疫応答の理解と制御 (2017)
  • Author(s): 齊藤達哉
  • Organizer: 第69回日本細胞生物学会大会
  • Invited
• [Presentation] オルガネラ損傷により誘導される自然免疫応答の理解と制御 (2017)
  • Author(s): 齊藤達哉
  • Organizer: 第1回感覚免疫学研究会
  • Invited
• [Presentation] Understanding and manipulation of organelle-mediated innate immune response (2017)
  • Author(s): 齊藤達哉
  • Organizer: 第12回研究所ネットワーク国際シンポジウム「Driving Next-Generation Medicine: the Spirit of Pioneering Discovery in Medical Science」
  • Invited
• [Presentation] 生体防御応答を制御するオルガネラ・ゾーンの理解 (2017)
  • Author(s): 齊藤達哉
  • Organizer: 2017年度生命科学系学会合同年次大会（ConBio2017）
  • Invited
• [Presentation] NLRP3インフラマソーム活性化を阻害する化合物の同定 (2017)
  • Author(s): 齊藤達哉, 中山昌喜, 髙濵充寛
  • Organizer: 日本薬学会第137年会
  • Place of Presentation: 東北大学川内北キャンパス（宮城県仙台市）
• [Presentation] リソソーム損傷により引き起こされる自然免疫応答の制御メカニズム (2017)
  • Author(s): 齊藤達哉, 髙濵充寛
  • Organizer: 第90回日本薬理学会年会
  • Place of Presentation: 長崎新聞文化ホール（長崎県長崎市）
• [Presentation] オートファジーによるNLRP3インフラマソーム活性化の制御 (2016)
  • Author(s): 齊藤達哉，髙濱充寛
  • Organizer: 日本薬学会第136年会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-03-27
• [Presentation] フィトケミカルによる自然炎症の抑制 (2016)
  • Author(s): 齊藤達哉
  • Organizer: 第89回日本薬理学会年会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-03-11
• [Presentation] The roles of organelle communication in innate immune responses (2016)
  • Author(s): Tatsuya Saitoh
  • Organizer: 第45回日本免疫学会学術集会
  • Place of Presentation: 沖縄コンベンションセンター（沖縄県宜野湾市）
  • Invited
• [Presentation] Organelle Crosstalk Mediates Innate Immune Response (2016)
  • Author(s): Tatsuya Saitoh
  • Organizer: 第89回日本生化学会大会
  • Place of Presentation: 東北大学川内北キャンパス（宮城県仙台市）
  • Invited
• [Presentation] Role of mitochondria in regulation of innate immune response (2016)
  • Author(s): Tatsuya Saitoh
  • Organizer: The KSBMB International Conference 2016
  • Place of Presentation: Seoul (Korea)
  • Int'l Joint Research / Invited
• [Presentation] 大気汚染物質により惹起される炎症反応の理解と制御法開発 (2016)
  • Author(s): 齊藤達哉, 髙濵充寛, 三澤拓馬, 審良静男
  • Organizer: 第86回日本衛生学会学術総会
  • Place of Presentation: 旭川市民文化会館（北海道旭川市）
• [Presentation] Mitochondria mediate a host defense response to sindbis virus. (2015)
  • Author(s): Tatsuya Saitoh
  • Organizer: The 2015 American Society for Cell Biology Annual Meeting
  • Place of Presentation: San Diego, USA
  • Year and Date: 2015-12-15
  • Int'l Joint Research
• [Presentation] Mitochondrial damage induces antiviral innate immune response (2015)
  • Author(s): Tatsuya Saitoh, Tatsuya Kozaki, Shizuo Akira
  • Organizer: BMB2015 Biochemistry and Molecular Biology
  • Place of Presentation: 神戸ポートアイランド（兵庫県神戸市）
  • Year and Date: 2015-12-02
• [Presentation] TIPARP mediates a host defense response to sindbis virus (2015)
  • Author(s): Tatsuya Saitoh, Tatsuya Kozaki, Shizuo Akira
  • Organizer: The 63rd Annual Meeting of the Japanese Society for Virology
  • Place of Presentation: 福岡国際会議場（福岡県福岡市）
  • Year and Date: 2015-11-24
• [Presentation] NLRP3インフラマソーム活性化を阻害する化合物の同定 (2015)
  • Author(s): 齊藤達哉
  • Organizer: 第68回日本薬理学会西南部会
  • Place of Presentation: 海峡メッセ下関（山口県下関市）
  • Year and Date: 2015-11-21
• [Presentation] オートファジー関連因子による自然免疫応答の制御 (2015)
  • Author(s): 齊藤達哉
  • Organizer: 第9 回オートファジー研究会
  • Place of Presentation: 淡路夢舞台国際会議場（兵庫県淡路市）
  • Year and Date: 2015-11-17
  • Invited
• [Presentation] 感染防御における自然免疫の役割 (2015)
  • Author(s): 齊藤達哉
  • Organizer: 第47回日本小児感染症学会総会・学術集会
  • Place of Presentation: ザ・セレクトン福島（福島県福島市）
  • Year and Date: 2015-11-01
  • Invited
• [Presentation] Mitochondrial damage elicits a viral RNA-degrading innate immune response. (2015)
  • Author(s): Tatsuya Saitoh
  • Organizer: Japan Australia Meeting on Cell Death
  • Place of Presentation: Melbourne, Australia
  • Year and Date: 2015-10-22
  • Int'l Joint Research
• [Presentation] ミトコンドリア損傷に応じて誘導される新たな自然免疫応答 (2015)
  • Author(s): 齊藤達哉
  • Organizer: 第24回日本Cell Death学会学術集会
  • Place of Presentation: 大阪大学会館（大阪府豊中市）
  • Year and Date: 2015-07-11
  • Invited
• [Presentation] ミトコンドリアを起点とする新たな自然免疫応答の同定 (2015)
  • Author(s): 児崎達哉，高濱充寛，齊藤達哉
  • Organizer: 第14回四国免疫フォーラム
  • Place of Presentation: 愛媛大学医学部（愛媛県東温市）
  • Year and Date: 2015-06-20
• [Presentation] ミトコンドリアの損傷はウイルスRNAを分解に導く自然免疫応答を惹起する (2015)
  • Author(s): 齊藤達哉
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学（神戸）
  • Year and Date: 2015-03-27
  • Invited
• [Presentation] NLRP3インフラマソーム活性化を阻害する化合物の同定 (2015)
  • Author(s): 齊藤達哉，三澤拓馬，審良静男
  • Organizer: 第88回日本薬理学会年会
  • Place of Presentation: 名古屋国際会議場（名古屋）
  • Year and Date: 2015-03-20
• [Presentation] Regulation of innate immune response by autophagy. (2014)
  • Author(s): Tatsuya Saitoh
  • Organizer: The 16th Northeastern Asian Symposium “Autophagy: From Basic to Medicine”
  • Place of Presentation: Pusan（Korea）
  • Year and Date: 2014-12-20
• [Presentation] Role of organelle in regulation of innate immune response (2014)
  • Author(s): Tatsuya Saitoh, Takuma Misawa, Tatsuya Kozaki, Shizuo Akira
  • Organizer: 第43回日本免疫学会総会
  • Place of Presentation: 国立京都国際会館（京都）
  • Year and Date: 2014-12-12
• [Presentation] オートファジー関連因子による自然免疫応答の制御 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 第8回オートファジー研究会
  • Place of Presentation: シャトレーゼガトーキングダムサッポロ（札幌）
  • Year and Date: 2014-11-11
  • Invited
• [Presentation] Regulation of innate immune response by autophagy. (2014)
  • Author(s): Tatsuya Saitoh
  • Organizer: The 2014 Fall Conference of the Korean Association of Immunologists
  • Place of Presentation: Seoul（Korea）
  • Year and Date: 2014-11-07
  • Invited
• [Presentation] NLRP3インフラマソームを介した炎症応答の理解とその制御 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 日本リウマチ学会 第1回アニュアルベーシックコースレクチャー
  • Place of Presentation: アキバプラザ（東京）
  • Year and Date: 2014-10-25
  • Invited
• [Presentation] 自然免疫応答における細胞内微細構造体の役割 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 第87回日本生化学会大会
  • Place of Presentation: 国立京都国際会館（京都）
  • Year and Date: 2014-10-17
  • Invited
• [Presentation] 痛風発作の分子機構 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 日本痛風・核酸代謝学会 第25回痛風研修会
  • Place of Presentation: 東京慈恵会医科大学（東京）
  • Year and Date: 2014-09-07
  • Invited
• [Presentation] 自然免疫応答の制御におけるオートファジーの役割 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 日本病態プロテアーゼ学会
  • Place of Presentation: 千里ライフサイエンスセンター（豊中）
  • Year and Date: 2014-08-08
  • Invited
• [Presentation] NLRP3インフラマソームを介した炎症応答の理解とその制御 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 第23回日本Cell Death学会学術集会
  • Place of Presentation: 東京医科歯科大学（東京）
  • Year and Date: 2014-07-19
  • Invited
• [Presentation] Understanding and manipulation of NLRP3-inflammasome. (2014)
  • Author(s): Tatsuya Saitoh
  • Organizer: The 22nd International Symposium on Molecular Cell Biology of Macrophages
  • Place of Presentation: Kobe（Ｊａｐａｎ）
  • Year and Date: 2014-06-02
  • Invited
• [Presentation] NLRP3インフラマソームと炎症性疾患 (2014)
  • Author(s): 齊藤達哉
  • Organizer: 第58回日本リウマチ学会総会・学術集会
  • Place of Presentation: グランドプリンスホテル新高輪（東京）
  • Year and Date: 2014-04-25
  • Invited
• [Book] Advances in Experimental Medicine and Biology 997 (2017)
  • Author(s): Misawa T, Takahama M, Saitoh T.
  • Total Pages: 257
  • Publisher: Springer
• [Book] 日本臨床 増刊号 高尿酸血症・低尿酸血症 Vol.74, No.9 (2016)
  • Author(s): 藤森 新, 山中 寿, 箱田 雅之, 谷口 敦夫, 細山田 真, 髙濵 充寛, 齊藤 達哉, 森崎 隆幸, 森崎 裕子, 久原 とみ子, 安西 尚彦, 大谷 真由, 降幡 知巳, 佐藤 啓造, 藤城 雅也, 李 暁鵬, 勝又 義直, 中村 真希子, 市田 公美, 東 幸仁 他
  • Total Pages: 464
  • Publisher: 日本臨牀社
• [Book] 実験医学 増刊 細胞死 (2016)
  • Author(s): 浅野謙一，阿部理一郎，池田史代，伊藤美智子，今井浩孝，植松智，植村紀仁，小川佳宏，小田（中橋）ちぐさ，勝山朋紀，榧垣伸彦，河村佳見，齊藤達哉，坂口翔太，澤田雅人，澤本和延，七田崇，渋谷彰，清水重臣，進藤綾大，他
  • Total Pages: 205
  • Publisher: 羊土社
• [Book] 高尿酸血症・痛風 別冊 診断と治療のABC 105 (2016)
  • Author(s): 寺井千尋，鎌谷直之，箱田雅之，細谷龍男，山本徹也，市田公美，大内基司，森崎隆幸，齊藤達哉，大野岩男，嶺尾郁夫，桑原政成，中山昌喜，東幸仁，谷口敦夫，瀬戸洋平，益田郁子，藤森新，森脇優司，他
  • Total Pages: 195
  • Publisher: 最新医学社
• [Book] ここまで明らかになった！尿酸代謝ワールドと高尿酸血症の病態解明～診療と医学の最前線～ (2015)
  • Author(s): 藏城雅文，南勲，小川佳宏，福原淳範，齊藤達哉，三澤拓馬，審良静男，小島淳，小川久雄，筒井裕之，庭野慎一，阿古潤哉，諸岡俊文，野出孝一，新井康之，山下浩平，櫛山暁史，西澤徹，野村昌作，西澤均，他
  • Total Pages: 159
  • Publisher: メディカルレビュー社