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The risk factor of malnutrition in head and neck cancer patients undergoing chemoradiotherapy

Research Project

Project/Area Number 26750042
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits
Research InstitutionThe University of Tokushima

Principal Investigator

YASUI Sonoko  徳島大学, 大学院医歯薬学研究部, 助教 (30716634)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords頭頸部癌 / 化学放射線療法 / 低栄養 / 栄養評価 / BIA / 栄養
Outline of Final Research Achievements

(1) We measured the time-course change of body composition by bioelectrical impedance analysis. We compared the body composition before treatment and 8 weeks after treatment. Although the body weight and skeletal muscle mass decreased significantly, there was no significant difference in body fat mass. (2) We classified the patients into two groups by high and low creatinine height index (CHI). In low CHI group, there was higher ratio of severe hematological toxicity, more delayed days of radiotherapy, and less survival rate. In this study, although we could not elucidate the factor of muscle mass reduction, our results suggested the low muscle mass at pre-treatment was likely to associate to severe hematological toxicity and the interruption of treatment.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (2 results)

All 2016

All Presentation (2 results)

  • [Presentation] 頭頸部癌化学放射線療法において治療開始時のクレアチニン身長係数が有害事象や治療中断にあたえる影響2016

    • Author(s)
      安井苑子、谷村真優、松原あつみ、堤理恵、谷佳子、松村晃子、島田亜紀、阪上浩、武田憲昭、濵田康弘
    • Organizer
      第31回日本静脈経腸栄養学会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-02-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] 頭頸部癌化学放射線療法において治療開始時のクレアチニン身長係数が有害事象に与える影響2016

    • Author(s)
      久保みゆ、安井苑子、谷村真優、松原あつみ、堤理恵、谷佳子、松村晃子、島田亜紀、阪上浩、武田憲昭、濵田康弘
    • Organizer
      第19回日本病態栄養学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-01-10
    • Related Report
      2015 Annual Research Report

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Published: 2014-04-04   Modified: 2017-05-10  

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