| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
To compare the effects of a low carbohydrate and high fat diet with a traditional high carbohydrate and low fat diet on markers of blood glucose and renal function in the rats of diabetic nephropathy. In this study, high fat diet reduced renal function and injured renal tissue more than high carbohydrate diet, even under energy restriction conditions. The high fat diet induced the ectopic fat depots in the proximal tubular cells in the diabetic nephropathy model rats. These findings suggest that high fat diet not recommended in diabetic nephropathy.
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