Search of foods inhibiting lipoxygenase for prevention of allergic disease
Project/Area Number |
26750049
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Eating habits
|
Research Institution | Okayama Prefectural University |
Principal Investigator |
Kawakami Yuki 岡山県立大学, 保健福祉学部, 准教授 (30453202)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | リポキシゲナーゼ / 食品 / 抗アレルギー作用 |
Outline of Final Research Achievements |
5-Lipoxygenase is an enzyme that catalyzes formation of leukotrienes. Leukotrienes are implicated in inflammatory processes and allergic reaction such as asthma. We evaluated the inhibitory effect of various foods on 5-lipoxygenase activity. We found that nutmeg contained a potent inhibitor of 5-lipoxygenase. We identified an inhibitor of 5-lipoxygenase in nutmeg and established an efficient extraction protocol.
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Report
(4 results)
Research Products
(2 results)