| Project/Area Number |
26750159
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
Hayakawa Satoshi 岡山大学, 大学院自然科学研究科, 教授 (20263618)
Yoshioka Tomohiko 岡山大学, 大学院自然科学研究科, 準教授 (50452016)
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| Research Collaborator |
Nagano Yasuyuki
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | リン酸カルシウム / 銅 / 骨補填材 / 骨伝導 / 血管新生 / 骨誘導 |
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| Outline of Final Research Achievements |
With the intent to combine osteoconductivity with angiogenic property, the present study aimed to fabricate copper and silicon co-doped β-tricalcium phosphates (β-TCP).
Copper-doped β-TCP(s) were successfully synthesized via both solid-state and liquid-phase reaction. In addition, the effect of copper on the dissolution behaviors of copper TCP (CuTCP) was also investigated. The incorporation of copper in the β-TCP resulted in a decrease in the dissolution rate of CuTCP, which was caused by a rate-determining dissolution process of a disordered phase around the CuTCP.
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