Elucidation of neural mechanisms in electrical therapy for musculoskeletal pain

• Project/Area Number: 26750180
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: University of Toyama
• Principal Investigator: Takamoto Kouich 富山大学, 大学院医学薬学研究部(医学), 客員助教 (00553116)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 電気刺激療法 / 筋骨格系疼痛 / 近赤外分光法

Outline of Final Research Achievements

We investigated effects of electrical stimulation at myofascial trigger point (MTrP) in patients with neck pain on cerebral hemodynamic responses using near infrared spectroscopy (NIRS). The patients with neck pain were randomly assigned to 2 groups (stimulation at MTrP group, Stimulation at Non-MTrP group). Electrical Stimulation at TP in patients with neck pain significantly improved subjective feeling of pain and increased Pain pressure threshold after stimulation compared with stimulation at Non-TP. Oxy-Hb concentration in the prefrontal cortex was significantly decreased during stimulation at TP compared with stimulation at Non-TP.

Research Products

• [Journal Article] Effects of compression at myofascial trigger points in patients with acute low back pain: A randomized controlled trial. (2015)
  • Author(s): Takamoto K, Bito I, Urakawa S, Sakai S, Kigawa M, Ono T, Nishijo H.
  • Journal Title: Eur J Pain Volume: - Issue: 8 Pages: 1186-1196
  • DOI: 10.1002/ejp.694
  • Peer Reviewed
• [Journal Article] Manual therapy ameliorates delayed-onset muscle soreness and alters muscle metabolites in rats (2015)
  • Author(s): Urakawa S, Takamoto K, Kanemoto M, Nakamura T, Sakai S, Matsuda T, Taguchi T, Mizumura K, Ono T, Nishijo H
  • Journal Title: Physiol Rep Volume: 3 Issue: 2 Pages: 2-2
  • DOI: 10.14814/phy2.12279
  • Peer Reviewed / Open Access
• [Journal Article] Selective Medial Prefrontal Cortex Responses During Live Mutual Gaze Interactions in Human Infants: An fNIRS Study. (2014)
  • Author(s): Urakawa S, Takamoto K, Ishikawa A, Ono T, Nishijo H.
  • Journal Title: Brain Topogr Volume: -
  • Peer Reviewed
• [Journal Article] Cerebral functional imaging using near-infrared spectroscopy during repeated performances of motor rehabilitation tasks tested on healthy subjects. (2014)
  • Author(s): Ishikuro K, Urakawa S, Takamoto K, Ishikawa A, Ono T, Nishijo N.
  • Journal Title: Front Hum Neurosci Volume: 8 Pages: 292-292
  • DOI: 10.3389/fnhum.2014.00292
  • Peer Reviewed / Open Access
• [Presentation] トリガーポイント圧迫強度の違いが脳血行動態に及ぼす影響. (2015)
  • Author(s): 児玉香菜絵, 高本考一, 浦川将, 酒井重数, 西条寿夫, 小野武年.
  • Organizer: 第24回日本柔道整復接骨医学会
  • Place of Presentation: 新潟
  • Year and Date: 2015-11-07
• [Presentation] 頚部痛に対するトリガーポイント圧迫の治療効果の検討. (2015)
  • Author(s): 石川なるみ,福留旺, 仲岡誠紘, 高本考一, 西条寿夫,尾藤何時夢.
  • Organizer: 第24回日本柔道整復接骨医学会
  • Place of Presentation: 新潟
  • Year and Date: 2015-11-07
• [Presentation] Cerebral hemodynamic responses during lower limb exercise assisted by robot suit Hybrid Assistive Limb (HAL). (2015)
  • Author(s): Yuya Ota, Susumu Urakawa, Kouich Takamoto, Taketoshi Ono, Hisao Nishijo.
  • Organizer: The 38th Annual Meeting of the Japan Neuroscience Society.
  • Place of Presentation: 神戸
  • Year and Date: 2015-07-28