| Project/Area Number |
26750181
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Shinshu University |
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Principal Investigator |
YAMASAKI Saeko 信州大学, 学術研究院医学系(医学部附属病院), 助教 (50623914)
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| Research Collaborator |
EBISAWA Soichiro 信州大学, 医学部附属病院, 講師(特定雇用) (50645439)
KASHIMA Yuichiro 信州大学, 学術研究院医学系(医学部附属病院), 助教 (70545722)
IKEDA Uichi 信州大学, 医学部, 特任教授 (30221063)
KUWAHARA Koichiro 信州大学, 学術研究院医学系, 教授 (30402887)
AONO Minako 信州大学, 医学部附属病院, 技術補佐員
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 循環器、高血圧 / 心臓リハビリテーション / 運動療法 / 福祉 / 閉塞性動脈硬化症 / 循環器内科 / 高血圧 / 循環器・高血圧 / リハビリテーション |
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| Outline of Final Research Achievements |
Peripheral artery disease (PAD) is an atherosclerotic disease. PAD patients often have other cardiovascular disease and poor prognosis. Exercise is effective for claudication and prognosis of patients with PAD. Few hospitals give supervised exercise therapy for PAD and report why exercise is effective for PAD. This study enrolled twenty five PAD patients with claudication. The levels of diacron-reactive oxygen metabolite (d-ROM: an oxidative stress marker), ankle-brachial index (ABI), and maximum walking distance at baseline and at 3 months after endovascular therapy (EVT) were measured. As compared with baseline values, the maximum walking distance, ABI and d-ROM improved significantly after EVT (109.9±104.2 vs. 313.7±271.8 m; 0.61±0.15 vs. 0.91±0.13; 472.8±64.8 vs. 390.2 ±46.7 U.CARR).
We encouraged supervised exercise therapy and explained their effect. We succeeded in increasing cardiac rehabilitation.
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