The effects of corticotropin releasing hormone on motor learning.

Research Project

Project/Area Number	26750240
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Developmental mechanisms and the body works
Research Institution	Tokai University
Principal Investigator	TAKEUCHI Eri 東海大学, 創造科学技術研究機構, 特定研究員 (70712777)
Project Period (FY)	2014-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	コルチコトロピン放出ホルモン / 運動学習
Outline of Final Research Achievements	In this study, we investigated the effect of corticotropin releasing hormone (CRH) on motor learning in vivo. We found that the acquisition of motor learning was enhanced in the rats injected CRH into the cerebellum. On the other hand, the acquisition of motor learning was impaired in the rats injected with CRH receptor antagonist. Our results suggest that exogenous CRH enhances the motor learning and endogenous CRH are needed for the motor learning in the cerebellum.

Report

(3 results)