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Spontaneous motion and deformation of active matters: toward understanding of cell motility

Research Project

Project/Area Number 26800219
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Biological physics/Chemical physics/Soft matter physics
Research InstitutionTohoku University

Principal Investigator

Yoshinaga Natsuhiko  東北大学, 原子分子材料科学高等研究機構, 准教授 (90548835)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsアクティブマター / 非平衡物理 / 非線形ダイナミックス / 生物物理 / 流体力学 / マランゴニ効果 / 細胞運動 / ソフトマター / 非平衡相転移
Outline of Final Research Achievements

Spontaneous motion has attracted lots of attention for its potential application to biological problems such as cell motility. Recently, several experiments showing spontaneous motion driven by chemical reactions have been proposed and revealed the underlying mechanism of the motion. Accordingly, several simple theoretical models have been extensively studied such as active Brownian particles, squirmers, and self-thermophoretic swimmers. We theoretically derive nonlinear equations showing a transition between stationary and motile states driven due to chemical reactions. A particular focus is on how destabilisation of an isotropic concentration field through hydrodynamic flow. Due to self-propulsive motion and flow around the drop, a spherical shape becomes unstable.
We have also clarified that hydrodynamic interactions and the interaction mediated by a concentration field give rise to collective behaviors such as motility-induced phase separation, global polar state, and clustering.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (35 results)

All 2017 2016 2015 2014 Other

All Int'l Joint Research (3 results) Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (23 results) (of which Int'l Joint Research: 13 results,  Invited: 12 results) Book (1 results) Remarks (6 results)

  • [Int'l Joint Research] Bristol University(英国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Bristol University(英国)

    • Related Report
      2015 Research-status Report
  • [Int'l Joint Research] University of Oxford/University of California/University College London(イギリス、アメリカ)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Collision between chemically-driven self-propelled drops2016

    • Author(s)
      Shunsuke Yabunaka and Natsuhiko Yoshinaga
    • Journal Title

      Journal of Fluid Mechanics

      Volume: 809 Pages: 205-233

    • DOI

      10.1017/jfm.2016.602

    • NAID

      130006245876

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] General criteria for determining rotation or oscillation in a two-dimensional axisymmetric system2015

    • Author(s)
      Yuki Koyano, Natsuhiko Yoshinaga, and Hiroyuki Kitahata
    • Journal Title

      Journal of Chemical Physics

      Volume: 143 Issue: 1 Pages: 014117-014117

    • DOI

      10.1063/1.4923421

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] アクティブ液晶の自発運動と変形2017

    • Author(s)
      義永 那津人
    • Organizer
      日本物理学会第72回年次大会
    • Place of Presentation
      大阪大学豊中キャンパス(大阪府豊中市)
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] Theory of Active Soft Materials2017

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      The AIMR International Symposium 2017 (AMIS2017)
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2017-02-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Hydrodynamic Interaction and Collective Behaviors of Self-Propelled Particles and Drops2017

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      Gordon Research Conference: Complex Active & Adaptive Material Systems
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2017-01-29
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Hydrodynamics and Collective Behaviours of Self-Propelled Active Systems2017

    • Author(s)
      Natuhiko Yoshinaga
    • Organizer
      A3 Workshop on Soft Matter 2017
    • Place of Presentation
      Tohoku University, Japan
    • Year and Date
      2017-01-18
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The Hydrodynamic Interaction and Collective Behaviours of Self-Propelled Particles and Drops2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      Current and Future Perspectives in Active Matter
    • Place of Presentation
      The University of Tokyo, Japan
    • Year and Date
      2016-10-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 化学反応によって駆動される液滴の自発運動と集団挙動2016

    • Author(s)
      義永 那津人
    • Organizer
      集団ダイナミクスに現れる時空間パターンの数理
    • Place of Presentation
      京都大学数理解析研究所(京都府京都市)
    • Year and Date
      2016-10-12
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 化学反応による液滴の運動とアクティブ液晶2016

    • Author(s)
      義永 那津人
    • Organizer
      日本物理学会2016年秋季大会
    • Place of Presentation
      金沢大学(石川県金沢市)
    • Year and Date
      2016-09-13
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 自己駆動粒子とそれらの集団運動における流体力学の役割2016

    • Author(s)
      義永 那津人
    • Organizer
      札幌非線形科学研究会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2016-08-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] The Collective Behaviors of Self-Propelled Particles and Drops through hydrodynamic interactions2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      Patterns and Waves 2016
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2016-08-01
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The Collective Behaviors of Self-Propelled Particles and Drops through hydrodynamic interactions2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      Daynamics Days 201
    • Place of Presentation
      Corfu, Greece
    • Year and Date
      2016-06-06
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] The Hydrodynamic Interaction and Collective Behaviors of Self-Propelled Particles and Drops2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      Emergent dynamics of out-of-equilibrium colloidal systems at nano- to microscales
    • Place of Presentation
      CECAM-HQ-EPFL, Lausanne, Switzerland
    • Year and Date
      2016-04-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Hydrodynamics and Collective Behaviors of Self-Propelled Particles and Drops in Active Suspensions2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      The A3 mini-Workshop on Soft matter
    • Place of Presentation
      Beihang University, Beijing, China
    • Year and Date
      2016-03-23
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Janus粒子の集団運動2016

    • Author(s)
      義永那津人
    • Organizer
      日本物理学会 第71回年次大会
    • Place of Presentation
      東北学院大学泉キャンパス
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
  • [Presentation] Theory of Active Materials2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      The AIMR International Symposium 2016 (AMIS2016)
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2016-02-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] アクティブマターの数理モデル2016

    • Author(s)
      義永那津人
    • Organizer
      アクティブマター研究会2016
    • Place of Presentation
      九州大学箱崎キャンパス国際ホール
    • Year and Date
      2016-01-22
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] The hydrodynamic interaction and collective behaviours of self-propelled particles and drops2016

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      International Workshop on Hydrodynamic Flows in/of Cells
    • Place of Presentation
      Tokyo Metropolitan University, Japan
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Self-propulsive motion and deformation of a chemically-driven drop2015

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      68th Annual Meeting of the APS Division of Fluid Dynamics
    • Place of Presentation
      Hynes Convention Center, Boston, USA
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Dynamics of Ordered Patterns and Defects2015

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      NanoMat 2015
    • Place of Presentation
      Campus de Beaulieu, Rennes, France
    • Year and Date
      2015-05-27
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Self-propulsion of a droplet: motility and deformation2015

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      The Ninth IMACS International Conference on Nonlinear Evolution Equations and Wave Phenomena: Computation and Theory
    • Place of Presentation
      University of Georgia, Athens, USA
    • Year and Date
      2015-04-01
    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 自発運動するヤヌス粒子の間の相互作用2015

    • Author(s)
      義永 那津人
    • Organizer
      日本物理学会第70回年次大会
    • Place of Presentation
      早稲田大学 (東京)
    • Year and Date
      2015-03-21 – 2015-03-24
    • Related Report
      2014 Research-status Report
  • [Presentation] 自発運動する粒子の間の相互作用2015

    • Author(s)
      義永 那津人
    • Organizer
      新学術領域「ゆらぎと構造の協奏」領域研究会 「アクティブ・マター研究の過去・現在・未来」
    • Place of Presentation
      東北大学 (仙台)
    • Year and Date
      2015-03-14 – 2015-03-15
    • Related Report
      2014 Research-status Report
  • [Presentation] Mechanics of active gels and spontaneous motion of droplets as biologically-motivated systems2014

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      RIMS International Conference: “Mathematical Challenge to a New Phase of Materials Science"
    • Place of Presentation
      北海道大学 電子科学研究所 (札幌)
    • Year and Date
      2014-08-04 – 2014-08-08
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Spontaneous motion and deformation of a droplet driven by chemical reaction2014

    • Author(s)
      Natsuhiko Yoshinaga
    • Organizer
      RIMS International Conference: “Sapporo summer conference on dynamics of patterns in materials science",
    • Place of Presentation
      京都大学 数理科学研究所 (京都)
    • Year and Date
      2014-07-31 – 2014-08-02
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] 材料表面の親水・親油の評価と制御設計 第5章 界面自由エネルギーから運動エネルギーへの変換 第7節 温度勾配が駆動する粒子の運動~ Ludwig-Soret effect~2016

    • Author(s)
      義永 那津人
    • Total Pages
      600
    • Publisher
      テクノシステム
    • Related Report
      2016 Annual Research Report
  • [Remarks] 研究代表者による研究内容に関するwebページ

    • URL

      http://www.wpi-aimr.tohoku.ac.jp/~yoshinaga/index.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] ResearcherID

    • URL

      http://www.researcherid.com/rid/G-3067-2011

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
  • [Remarks] ResearchGate

    • URL

      https://www.researchgate.net/profile/Natsuhiko_Yoshinaga

    • Related Report
      2016 Annual Research Report 2015 Research-status Report 2014 Research-status Report
  • [Remarks] 研究代表者による研究内容に関するwebページ

    • URL

      http://www.wpi-aimr.tohoku.ac.jp/~yoshinaga/

    • Related Report
      2015 Research-status Report
  • [Remarks] 研究内容に関するページ

    • URL

      http://www.wpi-aimr.tohoku.ac.jp/~yoshinaga/

    • Related Report
      2014 Research-status Report
  • [Remarks] Researcher ID

    • URL

      http://www.researcherid.com/rid/G-3067-2011

    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2022-02-16  

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