Coupling between order formation and motion of charged lipid membranes under nonequilibrium state
| Project/Area Number |
26800222
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biological physics/Chemical physics/Soft matter physics
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| Research Institution | Japan Advanced Institute of Science and Technology |
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Principal Investigator |
Shimokawa Naofumi 北陸先端科学技術大学院大学, 先端科学技術研究科, 助教 (20700181)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 相分離 / 膜変形 / 静電相互作用 / リポソーム / 脂質膜 / リン脂質 / ベシクル / 脂質二重膜 / 電場 / 変形 |
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| Outline of Final Research Achievements |
We investigated the phase separation and the spontaneous membrane deformation in charged lipid membranes consisting of negatively charged lipids and neutral lipids by experimental, theoretical, and numerical simulation methods. Moreover, we analyzed the fusion and motion of W/O emulsions under DC electric field. The formation of phase-separated structures and membrane morphological changes can be induced by controlling the electrostatic interaction between charged lipids. From these findings, we revealed the order formation under the electrostatic interactions. These obtained results are expected to lead to understandings of various biocellular functions and foundations of industrial applications.
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Report
(4 results)
Research Products
(89 results)
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[Presentation] 塩の添加が支配する荷電脂質膜の相分離2014
Author(s)
斉田拓巳、姫野泰輝、下川直史、高木昌宏
Organizer
日本物理学会2014年秋季大会
Place of Presentation
中部大学、春日井キャンパス、愛知県春日井市
Year and Date
2014-09-07 – 2014-09-10
Related Report
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