Selective C-H Bond Transformations via Single-Electron Transfer Processes
| Project/Area Number |
26810017
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Yoo Woo-Jin 東京大学, 理学(系)研究科(研究院), 助教 (70626077)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | single-electron transfer / visible light / C-H functionalization / cross-coupling / copper catalysis / photocatalysis / C-N bond formation / cross-coupling reaction / C-H bond activation / bifunctional catalyst / photocatalyst / aerobic oxidation |
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| Outline of Final Research Achievements |
The construction of complex organic molecules from simple chemical feedstocks through bond forming reactions is the essence of synthetic organic chemistry. Our research is focused on developing new methods and catalysts that can be used to produce carbon-carbon and carbon-heteroatom bonds in a sustainable manner. The basic concept we wish to utilize is the power of single-electron transfer processes to generate reactive organic and metal species. Over the past two years, we have developed several new catalyst systems that enabled efficient bond forming reactions. For example, we have found methods to selectively induce C-H cross-coupling reactions of amines, including amino acid derivatives. In addition, we have harnessed the visible light, as a clean sustainable source of energy, to mediate various types of cross-coupling reactions.
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Report
(3 results)
Research Products
(10 results)
