• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Investigation of LET dependence controller on Fricke gel dosimeter

Research Project

Project/Area Number 26820412
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Nuclear engineering
Research InstitutionKitasato University (2016-2017)
Institute of Physical and Chemical Research (2014-2015)

Principal Investigator

Maeyama Takuya  北里大学, 理学部, 助教 (70612125)

Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsゲル線量計 / フリッケゲル / ナノクレイ / MRI / 重粒子線 / 線量分布測定 / ナノコンポジットゲル / LET依存性 / フリッケ線量計 / 三次元線量分布 / LET効果 / 重粒子線治療 / 放射線化学 / 水溶液線量計
Outline of Final Research Achievements

We report a nanocomposite Fricke gel (NC-FG) dosimeter prepared using only Fe2+ and nanoclay in water, without any organic gelling agents. This dosimeter gels due to its thixotropic properties and exhibits linear energy transfer (LET)-independent radiological properties under carbon ion beam irradiation. The radiation sensitivity of this dosimeter was three times higher than that reported previously for a similar dosimeter containing gelatin. A further increase in the radiation sensitivity was observed upon addition of the hydrated electron scavenger N2O, suggesting the reduction of Fe3+ by a hydrated electron. LET-dependent variations of the contributions of OH radicals and hydrated electrons compensate each other in the oxidation yield of NC-FG. This is the main mechanism of the suppression of LET effcts in the Bragg peak compared to conventional Fricke dosimeters.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (27 results)

All 2018 2017 2016 2015 2014 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 2 results,  Open Access: 1 results) Presentation (17 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Polymer gel dosimeter with AQUAJOINT as hydrogel matrix2018

    • Author(s)
      Maeyama Takuya、Ishida Yasuhiro、Kudo Yoshihiro、Fukasaku Kazuaki、Ishikawa Kenichi L.、Fukunishi Nobuhisa
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 146 Pages: 121-125

    • DOI

      10.1016/j.radphyschem.2018.01.014

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fricke Gel Dosimeters2017

    • Author(s)
      前山 拓哉
    • Journal Title

      Japanese Journal of Medical Physics (Igakubutsuri)

      Volume: 37 Issue: 2 Pages: 99-106

    • DOI

      10.11323/jjmp.37.2_99

    • NAID

      130006943057

    • ISSN
      1345-5354, 2186-9634
    • Related Report
      2017 Annual Research Report
  • [Journal Article] Organic-Gelatin-Free Nanocomposite Fricke Gel Dosimeter.2017

    • Author(s)
      T. Maeyama, N. Fukunishi, K. L. Ishikawa, K. Fukasaku, S. Fukuda
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 121 Issue: 16 Pages: 4238-4246

    • DOI

      10.1021/acs.jpcb.6b11936

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Radiological properties of nanocomposite Fricke gel dosimeters for heavy ion beams2016

    • Author(s)
      Maeyama, T. Fukunishi, N. Ishikawa, K. L. Fukasaku, K. Fukuda, S.
    • Journal Title

      Journal of Radiation Research

      Volume: 1 Issue: 3 Pages: 1-7

    • DOI

      10.1093/jrr/rrw025

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Comparison between Monte Carlo simulation and measurement with a 3D polymer gel dosimeter for dose distributions in biological samples2015

    • Author(s)
      T Furuta, T Maeyama, K L Ishikawa, N Fukunishi, K Fukasaku, S Takagi, S Noda, R Himeno and S Hayashi
    • Journal Title

      Physics in Medicine and Biology

      Volume: 60 Issue: 16 Pages: 6531-6546

    • DOI

      10.1088/0031-9155/60/16/6531

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Radiological characteristics of MRI-based VIP polymer gel under carbon beam irradiation.2015

    • Author(s)
      T. Maeyama, N. Fukunishi, K. L. Ishikawa, T. Furuta, K. Fukasaku, S. Takagi, S. Noda, R. Himeno, and S. Fukuda
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 107 Pages: 7-11

    • DOI

      10.1016/j.radphyschem.2014.09.001

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] VIPポリマーゲル線量計による炭素線線量分布評価手法の検討2014

    • Author(s)
      前山 拓哉, 福西 暢尚, 石川 顕一, 古田 琢哉, 深作 和明, 高木 周, 野田 茂穂, 姫野 龍太郎, 福田茂一
    • Journal Title

      放射線化学

      Volume: 98 Pages: 11-15

    • Related Report
      2014 Research-status Report
  • [Presentation] MRI-based Gel Dosimeter for Heavy ion Beam Cancer Therapy2018

    • Author(s)
      Maeyama, T.
    • Organizer
      International Congress on Pure & Applied Chemistry (ICPAC) 2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 粒子線がん治療用三次元ゲル線量計の開発2017

    • Author(s)
      前山拓哉
    • Organizer
      放射線検出器の研究シーズと医療現場ニーズに関するシンポジウム(第 3 弾)~微小空間の線量測定に関する最新技術~
    • Place of Presentation
      首都大学東京荒川キャンパス 大視聴覚室 (東京都荒川区)
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] ゼラチンフリーナノコンポジットフリッケゲル線量計2016

    • Author(s)
      前山拓哉, 福西暢尚, 石川顕一, 深作和明, 福田茂一
    • Organizer
      第5回3Dゲル線量計研究会
    • Place of Presentation
      京都大学宇治キャンパス・ おうばくプラザ (京都府宇治市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
  • [Presentation] 高線量率小線源治療におけるポリマーゲル線量計の有用性2016

    • Author(s)
      江口昂, 渡邉祐介, 水上慎也, 前山拓哉, 林慎一郎, 寺崎剛史, 首藤宣昭, 五味勉
    • Organizer
      第5回3Dゲル線量計研究会
    • Place of Presentation
      京都大学宇治キャンパス・ おうばくプラザ (京都府宇治市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
  • [Presentation] Application and development of 3D chemical dosimetry using gel matrix for heavy ion beam2015

    • Author(s)
      T. Maeyama
    • Organizer
      The 213th RIKEN RIBF Nuclear Physics Seminar
    • Place of Presentation
      Nishina Hall, Nishina bldg, RIKEN,Saitama
    • Year and Date
      2015-12-22
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] AQUAJOINTポリマーゲル線量計2015

    • Author(s)
      前山拓哉 石田康博 工藤佳宏 深作和明 石川顕一 福西暢尚
    • Organizer
      第4回3Dゲル線量計研究会
    • Place of Presentation
      帝京大学板橋キャンパス(東京)
    • Year and Date
      2015-11-28
    • Related Report
      2015 Research-status Report
  • [Presentation] 有機ゲル化剤を含まないナノコンポジットフリッケゲル線量計2015

    • Author(s)
      前山拓哉 福西暢尚 石川顕一 深作和明 福田茂一
    • Organizer
      先端放射線化学シンポジウム
    • Place of Presentation
      浜名湖かんざんじ荘(静岡)
    • Year and Date
      2015-10-01
    • Related Report
      2015 Research-status Report
  • [Presentation] Radiological properties of the nanocomposite Fricke gel dosimeter for heavy ion beams2015

    • Author(s)
      Maeyama, T. Fukunishi, N. Ishikawa, K. L. Fukasaku, K. Fukuda, S.
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      Kyoto International Conference Center, Kyoto
    • Year and Date
      2015-05-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] LET依存性のないゲル線量計の開発2015

    • Author(s)
      前山拓哉 福西暢尚 石川顕一 深作和明 福田茂一
    • Organizer
      平成26年度 HIMAC共同利用研究 成果発表会
    • Place of Presentation
      ホテルポートプラザちば(千葉)
    • Year and Date
      2015-04-21
    • Related Report
      2015 Research-status Report
  • [Presentation] ナノコンポジットフリッケゲル線量計の組成条件の検討2014

    • Author(s)
      前山拓哉, 福西 暢尚, 石川 顕一,深作 和明, 福田茂一
    • Organizer
      第3回 3Dゲル線量計研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-11-23
    • Related Report
      2014 Research-status Report
  • [Presentation] Preliminary Result of Nanocomposite Fricke Gel Dosimeter2014

    • Author(s)
      T. Maeyama,N. Fukunishi, K. L. Ishikawa, K. Fukasaku, T. Furuta, S. Takagi, S. Noda, R. Himeno and S. Fukuda
    • Organizer
      The 5th Asia Pacific Symposium on Radiation Chemistry
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2014-09-11
    • Related Report
      2014 Research-status Report
  • [Presentation] A Diffusion-Free and Linear-Energy-Transfer-Independent Nanocomposite Frcike Gel Dosimeter.2014

    • Author(s)
      T. Maeyama, N. Fukunishi, K. L. Ishikawa, T. Furuta, K. Fukasaku, S. Takagi, S. Noda, R. Himeno, S. Fukuda.
    • Organizer
      The 2014 Gordon Research Conference on Radiation Chemistry
    • Place of Presentation
      NH, United States
    • Year and Date
      2014-07-14
    • Related Report
      2014 Research-status Report
  • [Presentation] A Diffusion-Free and Linear-Energy-Transfer-Independent Nanocomposite Frcike Gel Dosimeter.2014

    • Author(s)
      T. Maeyama, N. Fukunishi, K. L. Ishikawa, T. Furuta, K. Fukasaku, S. Takagi, S. Noda, R. Himeno, S. Fukuda.
    • Organizer
      The Gordon Research Seminar on Radiation Chemistry
    • Place of Presentation
      NH, United States
    • Year and Date
      2014-07-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 粒子線治療計画の三次元検証ツールとしてのナノコンポジットゲル線量計2014

    • Author(s)
      前山拓哉
    • Organizer
      第3回 重粒子線医工連携セミナー
    • Place of Presentation
      群馬大学
    • Year and Date
      2014-06-20
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 粒子線治療計画の三次元検証ツールとしてのナノコンポジットゲル線量計2014

    • Author(s)
      前山拓哉
    • Organizer
      理化学研究所 新技術説明会
    • Place of Presentation
      東京
    • Year and Date
      2014-06-13
    • Related Report
      2014 Research-status Report
  • [Presentation] LET依存性のないゲル線量計の開発2014

    • Author(s)
      前山 拓哉, 福西 暢尚, 石川 顕一, 古田 琢哉, 深作 和明, 高木 周, 野田 茂穂, 姫野 龍太郎, 福田茂一
    • Organizer
      平成25年度HIMAC 共同利用研究成果発表会
    • Place of Presentation
      千葉
    • Year and Date
      2014-04-22
    • Related Report
      2014 Research-status Report
  • [Presentation] LET依存性のないナノクレイ添加フリッケゲル線量計の開発2014

    • Author(s)
      前山 拓哉, 福西 暢尚, 石川 顕一, 古田 琢哉, 深作 和明, 高木 周, 野田 茂穂, 姫野 龍太郎, 福田茂一
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-13
    • Related Report
      2014 Research-status Report
  • [Remarks] 粒子線治療計画の 三次元検証ツールとしての ナノコンポジットゲル線量計

    • URL

      https://shingi.jst.go.jp/past_abst/abst/p/14/1407/riken2-8.pdf

    • Related Report
      2017 Annual Research Report
  • [Remarks] 粒子線がん治療用三次元ゲル線量計

    • URL

      http://www.riken.jp/outreach/ip/24154/

    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] 放射線線量測定ゲル、及びそれを放射線線量の計測材料として備える放射線線量計2014

    • Inventor(s)
      前山拓哉,福西暢尚,石川顕一,石田康博,相田卓三,深作和明,工藤
    • Industrial Property Rights Holder
      前山拓哉,福西暢尚,石川顕一,石田康博,相田卓三,深作和明,工藤
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-257836
    • Filing Date
      2014-12-19
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi