Analysis of intron-retaining form of DNA repair-related mRNAs
| Project/Area Number |
26840008
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Molecular biology
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| Research Institution | Hokkaido University (2015)
Kyoto University (2014) |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | スプライシング / ストレス応答 / RNAプロセシング / 遺伝子発現制御 / DNA損傷修復 |
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| Outline of Final Research Achievements |
Signal-induced splicing of nuclear intron-retaining RNA is a novel regulation mechanism of gene expression. However, it was still unclear what kinds of genes are controlled in a similar manner. Next generation sequencing and bioinformatics analyses revealed that some of promising candidates for novel intron-retaining RNAs are related to DNA damage response and regulated by DNA damage agents.
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Report
(3 results)
Research Products
(3 results)
