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Analysis of intron-retaining form of DNA repair-related mRNAs

Research Project

Project/Area Number 26840008
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Molecular biology
Research InstitutionHokkaido University (2015)
Kyoto University (2014)

Principal Investigator

Ninomiya Kensuke  北海道大学, 遺伝子病制御研究所, 助教 (00437279)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsスプライシング / ストレス応答 / RNAプロセシング / 遺伝子発現制御 / DNA損傷修復
Outline of Final Research Achievements

Signal-induced splicing of nuclear intron-retaining RNA is a novel regulation mechanism of gene expression. However, it was still unclear what kinds of genes are controlled in a similar manner. Next generation sequencing and bioinformatics analyses revealed that some of promising candidates for novel intron-retaining RNAs are related to DNA damage response and regulated by DNA damage agents.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2016 2015

All Presentation (2 results) Book (1 results)

  • [Presentation] 新規核内 intron-retaining RNA の探索2016

    • Author(s)
      二宮賢介、飯田慶、萩原正敏
    • Organizer
      北大・部局横断シンポジウム
    • Place of Presentation
      北海道大学フラテホール(北海道札幌市)
    • Year and Date
      2016-03-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] 新規核内 intron-retaining RNA の探索と解析2015

    • Author(s)
      二宮賢介、飯田慶 、佐久間真紀、佐古有季哉、萩原正敏
    • Organizer
      第17回RNA学会年会
    • Place of Presentation
      ホテルライフォート札幌(北海道札幌市)
    • Year and Date
      2015-07-15
    • Related Report
      2015 Annual Research Report
  • [Book] ヒートショック誘導性lncRNAと核内構造体 実験医学増刊「ノンコーディングRNAテキストブック」2015

    • Author(s)
      二宮賢介 廣瀬哲郎
    • Total Pages
      2
    • Publisher
      羊土社
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

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