| Project/Area Number |
26840044
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biophysics
|
|---|
| Research Institution | Hokuriku University (2015)
Hokkaido University (2014) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | フォトクロミック分子 / モータータンパク質 / ヌクレオチドアナログ |
|---|
| Outline of Final Research Achievements |
I have attempted to synthesize nucleotide derivatives which induce structural changes in a motor protein via photo-irradiations. Targe compounds were designed to consist of a covalently binding unit to the protein, a photo-responesive unit and a nucleotide unit. At this stage, I succeded in synthesizing several chimeric compounds consists of the covalently binding unit and the photo-responsive unit. However, the target compounds have not been obtained. Synethesis and purification methods of the final target nucleotide derivatives coupled with the chimeric units are under investigation.
|
