Micromechanics of cell division: mechanical measurement of the structure and feature of anaphase spindle
| Project/Area Number |
26840071
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cell biology
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| Research Institution | National Institute of Genetics |
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Principal Investigator |
Takagi Jun 国立遺伝学研究所, 新分野創造センター, 特任研究員 (40632196)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 細胞分裂 / 紡錘体 |
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| Outline of Final Research Achievements |
We measured the mechanical properties of the spindle, which is the structure for chromosome segregation during cell division. We found that the anaphase spindle is more flexible than the metaphase spindle against the external force along the spindle’s long axis, and that the link between chromosome and the spindle pole is mechanically flexible.
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Report
(3 results)
Research Products
(2 results)
