Micromechanics of cell division: mechanical measurement of the structure and feature of anaphase spindle

Research Project

Project/Area Number	26840071
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Cell biology
Research Institution	National Institute of Genetics
Principal Investigator	Takagi Jun 国立遺伝学研究所, 新分野創造センター, 特任研究員 (40632196)
Project Period (FY)	2014-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000) Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords	細胞分裂 / 紡錘体
Outline of Final Research Achievements	We measured the mechanical properties of the spindle, which is the structure for chromosome segregation during cell division. We found that the anaphase spindle is more flexible than the metaphase spindle against the external force along the spindle’s long axis, and that the link between chromosome and the spindle pole is mechanically flexible.

Report

(3 results)