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Mutual exclusive correlation analysis in iPS cell induction.

Research Project

Project/Area Number 26840076
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Developmental biology
Research InstitutionKyoto University

Principal Investigator

Takafusa Hikichi  京都大学, iPS細胞研究所, 研究員 (80392083)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsiPS細胞誘導 / 転写因子 / 遺伝子発現ネットワーク / シングルセル / iPS分化誘導 / 細胞特異的転写因子
Outline of Final Research Achievements

Gene expression mapping was performed using single cell analysis in neural progenitor cells and hepatic progenitor cells. As result, relationship between cell type specific genes and pluripotent stem cell genes was made clear. And several transcription factors which have important role in differentiation were enriched by comparison of gene correlation and histon modification analysis.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

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