| Project/Area Number |
26840086
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | Hirosaki University |
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Principal Investigator |
Sasabe Michiko 弘前大学, 農学生命科学部, 准教授 (00454380)
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| Research Collaborator |
OWADA Rie
SOTA Harutoshi
MASUKO Yuki
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 細胞分裂 / MAPK / CDK / プロテインキナーゼ / プロテインホスファターゼ / 細胞質分裂 / 植物 / リン酸化 / MAPキナーゼ / 細胞板 / 紡錘体 / フラグモプラスト / 微小管 |
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| Outline of Final Research Achievements |
To elucidate the molecular mechanisms of cell division in various organisms is important to reveal the developmental and differentiation processes in each organism. In this study, we aimed to identify the novel factors controlling plant cell division. The NACK-PQR pathway, which is a MAPK cascade unique to plant, is known as a key regulator of plant cytokinesis. This pathway is suppressed by CDKs during early M phase, and it is specifically activated during cytokinesis. Here we identified a novel type 2C protein phosphatase (PP2C) as a candidate that functions competitively to CDKs. This PP2C gene was dominantly expressed in the division zone of primary roots, emerging lateral roots and developing young leaves. Overexpression of this PP2C promoted the cell division but not the cell elongation in Arabidopsis plants, resulting in bigger seedlings with long roots. These results suggest this PP2C is involved in the cell division in plants.
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