| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
To deduce genomic and chromosomal evolution including the origins of microchromosomes in vertebrates, I constructed chromosome maps of 210 functional genes including 92 genes on microchromosomes in the chicken using FISH mapping for the extant fish in the most basal group of the ray-finned fish, the gray bichir (Polypterus senegalus), which has no microchromosomes. All of 18 genetic linkages of the chicken microchromosomes are highly conserved in Polypterus chromosomes. Moreover, the results of comparisons of chromosome synteny among the other vertebrates including Polypterus collectively suggest that the protokaryotypes of tetrapods and actinopterygians had contained many microchromosomes, each of whose linkages were conserved in the single microchromosomes of the chicken.
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