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Regulatory evolution of the turtle shell

Research Project

Project/Area Number 26840121
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Evolutionary biology
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

Pascual Anaya Juan  国立研究開発法人理化学研究所, 倉谷形態進化研究室, 研究員 (30594098)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords進化発生 / 遺伝 / 形態進化 / 比較ゲノム / 発生生物 / turtle shell / evolution / development / Evo-Devo
Outline of Final Research Achievements

Morphological innovations are those evolutionary novelties that appear without a clear ancestral structure, totally de novo. The turtle shell is a classical morphological innovation that has mesmerized researchers over a century, and despite deep studies addressing its origin, how turtles acquire the shell remains a mistery. During my project, I have utilized state-of-the-art technologies in order to tackle this problem. By using techniques of next generation sequencing, like ChIP-seq, I have been able to establish hundreds of candidate regultatory elements that seem to be turtle-specific and linked to the carapacial ridge, the embryonic structure that controls de development of the turtle carapace.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2015

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (3 results) (of which Invited: 3 results)

  • [Journal Article] The evolutionary origin of the turtle shell grounded on the axial arrest of the embryonic rib cage.2015

    • Author(s)
      Hirasawa, T., Pascual-Anaya, J., Kamezaki, N., Taniguchi, N., Mine, K., and Kuratani, S.
    • Journal Title

      J. Exp. Zool. (Mol. Dev. Evol.

      Volume: 324 Issue: 3 Pages: 194-207

    • DOI

      10.1002/jez.b.22579

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative analysis of pleurodiran and cryptodiran turtle embryos depicts the molecular ground pattern of the turtle carapacial ridge2015

    • Author(s)
      Juan Pascual-Anaya, Tatsuya Hirasawa, Iori Sato, Shigehiro Kuraku, Shigeru Kuratani
    • Journal Title

      International Journal of Developmental Biology

      Volume: -

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Transcriptomics and epigenomics analyses of the development of the turtle shell2015

    • Author(s)
      Juan Pascual-Anaya
    • Organizer
      CABD Seminar
    • Place of Presentation
      Andalusian Center for Developmental Biology, Seville, Spain
    • Year and Date
      2015-04-28
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Transcriptomics and epigenomics analyses of the development of the turtle shell2015

    • Author(s)
      Juan Pascual-Anaya
    • Organizer
      Invited seminar
    • Place of Presentation
      Andalusian Center for Deveolpmental Biology, Sevilla, Spain
    • Year and Date
      2015-04-28
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Transcriptomics analysis of the development of the turtle shell2015

    • Author(s)
      Juan Pascual-Anaya
    • Organizer
      Reptile Evo-Devo
    • Place of Presentation
      University of Oxford, UK
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Invited

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Published: 2014-04-04   Modified: 2017-05-10  

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