An fMRI study of the neural basis of parental behavior based on physiological polymorphism

• Project/Area Number: 26840160
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied anthropology
• Research Institution: Tokyo Metropolitan University
• Principal Investigator: MADOKA NORIUCHI 首都大学東京, 人間健康科学研究科, 客員研究員 (20571897)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: fMRI / 養育行動 / 脳機能 / 育児 / 親子 / 生理的多型性 / 適応能 / 乳幼児 / ｆＭＲＩ / 幼児

Outline of Final Research Achievements

We investigated parental brain responses to two-year-old child’s feeding situation using fMRI. We also examined the activations of four regions associated with parenting motivation such as parental love including orbitofrontal cortex (OFC), periaqueductal gray, dorsal raphe nucleus, anterior insula cortex, and ventral pallidum.
We found that the OFC which plays a critical role in reward system and representing the value of a stimulus reward was significantly activated in mother’s brain, but not in father’s brain. Our findings suggest that well-balanced maternal brain mechanisms integrated by OFC provide effective adaptive responses in daily parenting.

Research Products

• [Journal Article] Brainstem Activity Predicts Attachment-Related Anxiety. (2018)
  • Author(s): Yoshiaki Kikuchi, Yohan Matsutani, Kumiko Mori, Kenji Hanada, Yuko Shirakawa, Maki Shirato, Madoka Noriuchi
  • Journal Title: Neuropsychiatry Volume: 8 Issue: 01 Pages: 324-334
  • DOI: 10.4172/neuropsychiatry.1000354
  • Peer Reviewed / Open Access
• [Journal Article] The Neural Basis of Self-Touch in a Pain-Free Situation. (2018)
  • Author(s): Yoshiaki Kikuchi, Maki Shirato, Akiko Machida, Toshie Inoue, Madoka Noriuchi
  • Journal Title: Neuropsychiatry Volume: 8 Issue: 01 Pages: 186-196
  • DOI: 10.4172/neuropsychiatry.1000340
  • Peer Reviewed / Open Access
• [Journal Article] マターナル・ブレイン‐その適応的メカニズム‐ (2016)
  • Author(s): 則内まどか，菊池吉晃
  • Journal Title: 日本生理人類学会誌 Volume: 21 Pages: 135-140
  • NAID: 130006189480
  • Peer Reviewed
• [Journal Article] The effect of hip-hop dance training on neural response to emotional stimuli. (2016)
  • Author(s): Hiroomi Sensui, Toshiya Nagamatsu, Atsushi Senoo, Reiko Miyamoto, Madoka Noriuchi, Toshihiko Fujimoto, Yoshiaki Kikuchi
  • Journal Title: 体力研究 Bulletin of the Physical Fitness Research Institute Volume: 114 Pages: 20-29
  • NAID: 130007404239
  • Peer Reviewed / Open Access
• [Journal Article] Memory and reward systems coproduce ‘nostalgic’ experiences in the brain. (2015)
  • Author(s): Kentaro Oba, Madoka Noriuchi, Tomoaki Atomi, Yoshiya Moriguchi, Yoshiaki Kikuchi
  • Journal Title: Social Cognitive and Affective Neuroscience Volume: 8 Issue: 7 Pages: 1069-1077
  • DOI: 10.1093/scan/nsv073
  • Peer Reviewed
• [Journal Article] Self-Recognition of One's Own Fall Recruits the Genuine Bodily Crisis-Related Brain Activity. (2014)
  • Author(s): Atomi T, Noriuchi M, Oba K, Atomi Y, Kikuchi Y
  • Journal Title: PLOS ONE Volume: 2014 Issue: 12 Pages: 1-2
  • DOI: 10.1371/journal.pone.0115303
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Maternal Love in the Brain. (2017)
  • Author(s): Madoka Noriuchi, Yoshiaki Kikuchi
  • Organizer: Pacific Rim International Conference on Disability and Diversity, 2017
  • Int'l Joint Research
• [Presentation] Maternal brain and parenting stress. (2017)
  • Author(s): Madoka Noriuchi, Kumiko Mori, Yoko Kamio, Yoshiaki Kikuchi
  • Organizer: International Behavioral Neuroscience Society 26th Annual Meeting
  • Int'l Joint Research
• [Presentation] Yearning for yesterday: Neural substrates of nostalgia. (2015)
  • Author(s): Kentaro Oba, Madoka Noriuchi, Yoshiaki Kikuchi
  • Organizer: The 12th International Congress of Physiological Anthropology
  • Place of Presentation: 東京ベイ幕張ホール （千葉県・千葉市）
  • Year and Date: 2015-10-27
  • Int'l Joint Research / Invited
• [Presentation] Maternal brain response to child feeding (2015)
  • Author(s): Madoka Noriuchi, Kumiko Mori, Yoko Kamio, Yoshiaki Kikuchi
  • Organizer: Organization for Human Brain Mapping 2015
  • Place of Presentation: Hawaii Convention Center, Honolulu, Hawaii, USA
  • Year and Date: 2015-06-17
• [Presentation] Mother’s brain activity and its correlation with the mother-to-infant bonding (2015)
  • Author(s): Kumiko Mori, Madoka Noriuchi, Yoshiaki Kikuchi
  • Organizer: Organization for Human Brain Mapping 2015
  • Place of Presentation: Hawaii Convention Center, Honolulu, Hawaii, USA
  • Year and Date: 2015-06-17
• [Presentation] 母親のわが子に対する愛着の神経基盤 －おやつ場面における脳活動－ (2014)
  • Author(s): 則内まどか，森久美子，神尾陽子，菊池吉晃
  • Organizer: 日本生理人類学会第70回大会
  • Place of Presentation: 九州大学大橋キャンパス（福岡県・福岡市）
  • Year and Date: 2014-06-21
• [Book] Yoshiaki Kikuchi, Madoka Noriuchi (2017)
  • Author(s): The selfish brain: What matters in my body, not yours? In Emotional Engineering volume 4. Edited by Fukuda S.
  • Total Pages: 10
  • Publisher: Springer International Publishing
  • ISBN: 9783319708027
• [Book] The Nostalgic Brain: Its Neural Basis and Positive Emotional Role in Resilience. In Emotional Engineering, Vol. 5. Edited by Fukuda S. (2017)
  • Author(s): Yoshiaki Kikuchi, Madoka Noriuchi
  • Total Pages: 11
  • Publisher: Springer International Publishing AG
• [Book] Neural basis of maternal love as a vital human emotion. In Emotional Engineering volume 4. Edited by Fukuda S. (2016)
  • Author(s): Yoshiaki Kikuchi, Madoka Noriuchi
  • Total Pages: 10
  • Publisher: Springer International Publishing
• [Book] Neural basis of maternal love as a vital human emotion. In Emotional Engineering. Edited by Fukuda S. (2016)
  • Author(s): Yoshiaki Kikuchi, Madoka Noriuchi
  • Publisher: Springer-Verlag
• [Book] 「脳」の項目（人間科学の百科事典 ４．脳と心、日本生理人類学会編、ISBN978-4-621-08830－2） (2015)
  • Author(s): 則内まどか
  • Total Pages: 802
  • Publisher: 丸善出版
• [Book] 「育児」の項目（人間科学の百科事典 ７．ヒトの営み、日本生理人類学会編、ISBN978-4-621-08830－2） (2015)
  • Author(s): 則内まどか
  • Total Pages: 802
  • Publisher: 丸善出版