Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Outline of Final Research Achievements |
For the advanced use of two novel enzymes PET hydrolase (PETase) and mono (hydroxyethyl) terephthalate (MHET) hydrolase (MHETase) found from a poly(ethylene terephthalate) (PET)-degrading bacterium, these enzymes have been functionally identified, developed for the abundant soluble protein expression, and functionally improved. As a result, detailed functions of PETase has been identified and PETase mutants with improved thermal stability has been obtained.
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