Novel insights into proteins controlling chromosome structure and gene expression in Archaea
| Project/Area Number |
26850057
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied microbiology
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| Research Institution | Osaka Dental University |
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Principal Investigator |
MARUYAMA Hugo 大阪歯科大学, 歯学部, 助教 (90610296)
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| Research Collaborator |
ATOMI Haruyuki 京都大学, 工学研究科, 教授
HIGASHIBATA Hiroki 東洋大学, 准教授
YAN Jie シンガポール大学, 教授
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | アーキア / 染色体タンパク質 / 遺伝子発現 / 染色体 |
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| Outline of Final Research Achievements |
Archaea constitutes the third domain of life. Although chromosome architecture of Archaea is believed to be a primitive version of eukaryotic chromosome system, control of gene expression is currently only understood as activation and repression by transcription factors. Archaeal proteins that control both chromosome architecture and gene expression are starting to be understood. In this research, I tried to elucidate the mechanism underlying this coordinated control of chromosome structure and function.
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Report
(4 results)
Research Products
(8 results)
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[Journal Article] Complete Genome Sequence of Rothia aeria Type Strain JCM 11412, Isolated from Air in the Russian Space Laboratory Mir.2016
Author(s)
Nambu T, Tsuzukibashi O, Uchibori S, Yamane K, Yamanaka T, Maruyama H, Wang PL, Mugita N, Morioka H, Takahashi K, Komasa Y, Mashimo C.
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Journal Title
Genome Announcements
Volume: 4
Issue: 6
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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