| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The expression mechanism of cellulase and xylanase genes in the filamentous fungus Talaromyces cellulolyticus (formerly Acremonium cellulolyticus) was investigated by (i) analyzing the transcriptional factors genes which showed homology with those in other filamentous fungi, (ii) screening of the novel transcriptional factors.
We found that tacA, tctA, and Hap complex genes contribute to expression of cellulase and xylanase genes. Although the novel transcriptional factors have not been obtained, the strain which has high homologous recombination efficiency and the important promoter regions for cellulase gene expression were isolated.
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