Screening and analysis of aromatic polymer-hydrolyzing enzymes
| Project/Area Number |
26850060
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied biochemistry
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| Research Institution | Osaka City University (2015-2016)
University of Tsukuba (2014) |
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Principal Investigator |
Oinuma Ken-Ichi 大阪市立大学, 大学院医学研究科, 助教 (20635619)
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| Research Collaborator |
TAKAYA Naoki
KANEKO Tatsuo
KIZAWA Yoshie
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 芳香族ポリマー / 加水分解酵素 / Aspergillus niger / 芳香族ポリマ－ |
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| Outline of Final Research Achievements |
Aromatic polymers are widely used in plastic industries. One property common to these polymers is their resistance to bio-degradation and, despite its importance, there are only a few reports on aromatic polymer-degrading microorganism or enzymes. In this study, we used 4CDP, a recently developed aromatic polymer, as a model substrate and screened for microorganisms or enzymes that can degrade aromatic polymers. We found that a fungus in the genus Aspergillus produces some enzyme that hydrolyzes 4CDP. Moreover, we succeeded in purifying the enzyme from an Aspergillus-originated material and identifying the gene encoding the enzyme. We expect that knowledge on this enzyme will contribute to development of aromatic polymer-recycling system, which is to be materialized in the future.
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Report
(4 results)
Research Products
(18 results)
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[Presentation] ゲノム情報に基づくアシネトバクター属臨床分離株の分子疫学解析2017
Author(s)
老沼 研一, 鈴木 仁人, 佐藤 佳奈子, 中家 清隆, 滝沢 恵津子, 仁木 誠, 仁木 満美子, 山田 康一, 柴山 恵吾, 掛屋 弘, 金子 幸弘
Organizer
第91回日本感染症学会総会・学術講演会
Place of Presentation
京王プラザホテル（東京都新宿区）
Year and Date
2017-04-06
Related Report
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[Presentation] POT法およびMLST法によるアシネトバクター属臨床分離株の遺伝子型解析2017
Author(s)
老沼 研一, 鈴木 仁人, 佐藤 佳奈子, 中家 清隆, 滝沢 恵津子, 仁木 誠, 仁木 満美子, 山田 康一, 柴山 恵吾, 掛屋 弘, 金子 幸弘
Organizer
第51回緑膿菌感染症研究会学術集会
Place of Presentation
レンブラントホテル大分（大分県大分市）
Year and Date
2017-02-10
Related Report
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[Presentation] 当院で血液培養より分離されたアシネトバクター属細菌の分子疫学解析2017
Author(s)
金子 幸弘, 老沼 研一, 佐藤 佳奈子, 鈴木 仁人, 柴山 恵吾, 滝沢 恵津子, 仁木 誠, 中家 清隆, 仁木 満美子, 山田 康一, 掛屋 弘
Organizer
第28回日本臨床微生物学会総会・学術集会
Place of Presentation
長崎ブリックホール, 長崎新聞文化ホール, 長崎県医師会館（長崎県長崎市）
Year and Date
2017-01-20
Related Report
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[Presentation] アシネトバクター属臨床分離株の薬剤感受性試験と分子疫学解析2016
Author(s)
老沼 研一, 佐藤 佳奈子, 鈴木 仁人, 柴山 恵吾, 滝沢 恵津子, 仁木 誠, 中家 清隆, 仁木 満美子, 山田 康一, 掛屋 弘, 金子 幸弘
Organizer
第59回日本感染症学会中日本地方会学術集会
Place of Presentation
沖縄コンベンションセンター, カルチャーリゾートフェストーネ（沖縄県宜野湾市）
Year and Date
2016-11-24
Related Report
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