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Relationship of carotenoids and fatty acid on the bioavailability

Research Project

Project/Area Number 26850076
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Food science
Research InstitutionHirosaki University

Principal Investigator

MAEDA HAYATO  弘前大学, 農学生命科学部, 准教授 (80507731)

Research Collaborator MIKAMI Shohei  弘前大学, 農学生命科学研究科
KODATE Mei  弘前大学, 農学生命科学研究科
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsカロテノイド / 脂肪酸 / 脂質 / 肥満 / キサントフィル / 抗酸化
Outline of Final Research Achievements

In this study, we examined the influence of fatty acids on the digestion and absorption of carotenoids. Absorption of Lutein and astaxanthin on small intestinal epithelial cell were influenced by fatty acid composition. On the other hand, fatty acid composition was not involved in regulation of the expression on related to carotenoids absorption factors in small intestine. Therefore, it was suggested that fatty acids affect to stabilization of micelles or release of carotenoids from micelles in the intestinal tract.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (34 results)

All 2017 2016 2015 2014 Other

All Journal Article (16 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 14 results,  Open Access: 12 results,  Acknowledgement Compliant: 1 results) Presentation (15 results) (of which Invited: 3 results) Book (1 results) Remarks (2 results)

  • [Journal Article] EPR imaging and HPLC characterization of the pigment-based organic free radical in black soybean seeds.2017

    • Author(s)
      Nakagawa K, Maeda H
    • Journal Title

      Free radical research

      Volume: 51 Issue: 2 Pages: 187-189

    • DOI

      10.1080/10715762.2017.1291940

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accumulation of proanthocyanidins and/or lignin deposition in buff-pigmented soybean seed coats may lead to frequent defective cracking.2017

    • Author(s)
      Senda M, Yamaguchi N, Hiraoka M, Kawada S, Iiyoshi R, Yamashita K, Sonoki T, Maeda H, Kawasaki M
    • Journal Title

      Planta

      Volume: 245 Issue: 3 Pages: 259-670

    • DOI

      10.1007/s00425-016-2638-8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dietary tuna dark muscle protein attenuates hepatic steatosis and increases serum high-density lipoprotein cholesterol in obese type-2 diabetic/obese KK-Ay Mice.2017

    • Author(s)
      Maeda H, Hosomi R, Fukuda M, Ikeda Y, Yoshida M, Fukunaga K
    • Journal Title

      Journal of food science

      Volume: 印刷中 Issue: 5 Pages: 1231-1238

    • DOI

      10.1111/1750-3841.13711

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] カロテノイドの機能性とその吸収に対する食品成分の影響.2017

    • Author(s)
      前多隼人, 小舘めい, 三上翔平
    • Journal Title

      アグリバイオ

      Volume: 1(4) Pages: 66-71

    • NAID

      40021807390

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Homojesterones: vinylogous analogues of jesterone from Helminthosporium velutinum TS282016

    • Author(s)
      M Arayama, S Uesugi, K Tanaka, H Maeda, T Nehira, K Kimura, M Hashimoto
    • Journal Title

      Tetrahedron

      Volume: 72(7) Issue: 7 Pages: 1031-1035

    • DOI

      10.1016/j.tet.2015.12.077

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Homopetasinic acid isolated from Diaporthe sp. strain 1308-052016

    • Author(s)
      A Ito, I Kumagai, M Maruyama, H Maeda, A Tonouchi, T Nehira, K Kimura, M Hashimoto
    • Journal Title

      Tetrahedron Letters

      Volume: 57(10) Issue: 10 Pages: 1117-1119

    • DOI

      10.1016/j.tetlet.2016.01.095

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fucoxanthinol, Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells2015

    • Author(s)
      H Maeda, S Kanno, M Kodate, M Hosokawa, K Miyashita
    • Journal Title

      Marine drugs

      Volume: 13(8) Issue: 8 Pages: 4799-4813

    • DOI

      10.3390/md13084799

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 地域資源からの機能性食品素材の探索2015

    • Author(s)
      前多隼人, 田宇, 福田麻理, 松本和浩
    • Journal Title

      日本機能性食品医用学会誌

      Volume: 9(2) Pages: 67-72

    • Related Report
      2015 Research-status Report
  • [Journal Article] Effect of calcium concentration in growth medium on oxalate content and evaluation of the role of guttation in the regulation of oxalate in eddo2015

    • Author(s)
      Islam, M.N., Maeda, H. and Kawasaki, M.
    • Journal Title

      Plant Production Science

      Volume: 18 Issue: 4 Pages: 464-470

    • DOI

      10.1626/pps.18.464

    • NAID

      130005099366

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Computation-Assisted Structural Elucidation of Epoxyroussoeone and Epoxyroussoedione Isolated from Roussoella japanensis KT16512015

    • Author(s)
      Y Honmura, H Takekawa, K Tanaka, H Maeda, T Nehira, W Hehre, M Hashimoto
    • Journal Title

      Journal of natural products

      Volume: 78(7) Issue: 7 Pages: 1505-1510

    • DOI

      10.1021/np500924n

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Isolation, ECD assisted structural analyses, biosynthetic discussions, and biological activities of epi-cochlioquinones D and its derivatives2015

    • Author(s)
      M Arayama, T Nehira, H Maeda, K Tanaka, H Miyagawa, T Ueno, S Hosokawa, M Hashimoto
    • Journal Title

      Tetrahedron

      Volume: 71(29) Issue: 29 Pages: 4788-4794

    • DOI

      10.1016/j.tet.2015.05.044

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha2015

    • Author(s)
      N Nanashima, K Horie, T Tomisawa, M Chiba, M Nakano, T Fujita, H Maeda, M Kitajima, S Takamagi, D Uchiyama, J Watanabe, T Nakamura, Y Kato
    • Journal Title

      Molecular nutrition & food research

      Volume: 59(12) Issue: 12 Pages: 2419-2431

    • DOI

      10.1002/mnfr.201500479

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Achaetolide-II isolated from Helminthosporium velutinum TS282015

    • Author(s)
      M Arayama, H Maeda, K Tanaka, N Takada, T Nehira, M Hashimoto
    • Journal Title

      Tetrahedron

      Volume: 71(41) Issue: 41 Pages: 7900-7905

    • DOI

      10.1016/j.tet.2015.08.013

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dietary cod protein decreases triacylglycerol accumulation and fatty acid desaturase indices in the liver of obese type-2 diabetic KK-Ay mice2015

    • Author(s)
      Maeda H, Hosomi R, Koizumi M, Toda Y, Mitsui M, Fukunaga K.
    • Journal Title

      Journal of Functional Foods

      Volume: 14 Pages: 87-94

    • DOI

      10.1016/j.jff.2015.01.038

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nutraceutical Effects of Fucoxanthin for Obesity and Diabetes Therapy: A Review2015

    • Author(s)
      Maeda H
    • Journal Title

      Journal of Oleo Science

      Volume: 64 Issue: 2 Pages: 125-132

    • DOI

      10.5650/jos.ess14226

    • NAID

      130004800108

    • ISSN
      1345-8957, 1347-3352
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relative and absolute structure of phomolide C2015

    • Author(s)
      Ito, A.; Maeda, H.; Tonouchi, A.; Hashimoto, M
    • Journal Title

      Biosci. Biotech. Biochem

      Volume: 79 Issue: 7 Pages: 1-3

    • DOI

      10.1080/09168451.2015.1015953

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] パプリカキサントフィルによる脂肪細胞での慢性炎症状態の改善作用2017

    • Author(s)
      三上翔平, 西野梓, 鷹羽武史, 眞岡孝至, 前多隼人
    • Organizer
      日本農芸化学会2017年度大会
    • Place of Presentation
      京都市京都女子大学
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] カシスアントシアニンによる KK-Ay マウスおよび RAW 264.7 細胞での慢性炎症抑制作用2017

    • Author(s)
      小舘めい, 西山広亮, 前多隼人
    • Organizer
      日本農芸化学会2017年度大会
    • Place of Presentation
      京都市京都女子大学
    • Related Report
      2016 Annual Research Report
  • [Presentation] α-リノレン酸高含有リン脂質による非アルコール性脂肪肝炎改善作用2016

    • Author(s)
      前多隼人, 堂黒翔太, 梶直人, 阿孫健一
    • Organizer
      日本脂質栄養学会第25回大会
    • Place of Presentation
      秋田市にぎわい交流館AU
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 食品に含まれるカロテノイドなどの色素成分の機能性研究2016

    • Author(s)
      前多隼人
    • Organizer
      日本油化学会第55回年会
    • Place of Presentation
      奈良市奈良女子大学
    • Year and Date
      2016-09-07
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] ショウジョウバエを用いた新規ながん予防食品探索法の開発2016

    • Author(s)
      永長一茂・前多隼人
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] フコキサンチンによる初代培養白色脂肪細胞でのUCP1発現調節作用2016

    • Author(s)
      小舘めい・菅野翔伍・前多隼人
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] パプリカ色素投与による食事性肥満マウスに対する効果、及び各種臓器へのカロテノイドの蓄積2016

    • Author(s)
      三上翔平・中村望・前多隼人
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 赤肉新品種リンゴの皮と果肉の機能性成分評価2016

    • Author(s)
      石川春奈, 福田麻理, 松本和浩, 前多隼人
    • Organizer
      平成28年度日本食品科学工学会東北支部大会
    • Place of Presentation
      秋田市秋田カレッジプラザ
    • Related Report
      2016 Annual Research Report
  • [Presentation] 種類の異なる魚肉タンパク質の投与による肥満モデルマウスの脂質代謝に対する効果2015

    • Author(s)
      前多隼人,福田麻理,戸田裕子,小泉光可,細見亮太,吉田宗弘,福永健治
    • Organizer
      日本食品科学工学会第62回大会
    • Place of Presentation
      京都大学
    • Year and Date
      2015-08-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 白身および赤身魚由来タンパク質の給餌がラットの脂質代謝に及ぼす影響2015

    • Author(s)
      戸田裕子,福田麻理,細見亮太,前多隼人,吉田宗弘,福永健治
    • Organizer
      日本食品科学工学会第62回大会
    • Place of Presentation
      京都大学
    • Year and Date
      2015-08-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 海藻に含まれるフコキサンチンを中心としたキサントフィルの機能性2015

    • Author(s)
      前多隼人
    • Organizer
      2015年度日本農芸化学会東北支部シンポジウム
    • Place of Presentation
      岩手大学
    • Year and Date
      2015-07-11
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] サケ卵巣膜の一般成分およびタンパク質抽出物の健康機能性の評価2014

    • Author(s)
      大塚錬, 細見亮太, 前多隼人, 千葉詩子, 吉田宗弘, 福永健治
    • Organizer
      2014年度日本水産学会秋季大会
    • Place of Presentation
      九州大学箱崎キャンパス(福岡)
    • Year and Date
      2014-09-19 – 2014-09-22
    • Related Report
      2014 Research-status Report
  • [Presentation] フコキサンチン及びテルペノイドの新規生理機能に関する研究2014

    • Author(s)
      前多 隼人,
    • Organizer
      日本油化学会 第53回年会
    • Place of Presentation
      ホテルロイトン札幌(札幌市)
    • Year and Date
      2014-09-09 – 2014-09-11
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] α-リノレン酸高含有リン脂質による食事性肥満改善作用2014

    • Author(s)
      堂黒翔太, 梶直人, 阿孫健一, 前多隼人
    • Organizer
      日本油化学会 第53回年会
    • Place of Presentation
      ホテルロイトン札幌(札幌市)
    • Year and Date
      2014-09-09 – 2014-09-11
    • Related Report
      2014 Research-status Report
  • [Presentation] 新品種玉ねぎ「さらさらゴールド」による血糖値上昇抑制効果2014

    • Author(s)
      前多 隼人, 荒尾 紗代, 塚田 愛, 庭野 吉己
    • Organizer
      第68回日本栄養・食糧学会大会
    • Place of Presentation
      酪農学園大学(江別市)
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Book] 季刊 栄養教諭 大学ブランドの食品開発 弘前大学における食の取り組み2014

    • Author(s)
      前多隼人
    • Publisher
      日本文教出版株式会社
    • Related Report
      2014 Research-status Report
  • [Remarks] 弘前大学農学生命科学部食料資源学科前多隼人

    • URL

      http://nature.cc.hirosaki-u.ac.jp/staff/hayato-maeda

    • Related Report
      2016 Annual Research Report
  • [Remarks] 前多隼人弘前大学研究者総覧

    • URL

      http://hue2.jm.hirosaki-u.ac.jp/html/100000068_ja.html

    • Related Report
      2016 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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