Mechanisms of changes in body temperature induced by intake of food components via thermo TRP channels
Project/Area Number |
26850086
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Food science
|
Research Institution | The University of Shiga Prefecture |
Principal Investigator |
Mori Noriyuki 滋賀県立大学, 人間文化学部, 助教 (90585184)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | TRPチャネル / 体温調節 / 食品成分 / マウス / 熱産生 / 食品 / アンタゴニスト |
Outline of Final Research Achievements |
In this study, to elucidate the mechanisms of changes in body temperature induced by food intake, we focused on thermo TRP channels that have been indicated to have physiological roles in a perception of temperature and examined changes in body temperatures induced by food components activating these channels with mice. We found that the intake of food components which activate TRPV1, TRPM8, and TRPA1, respectively, changed body temperatures with the activation-temperature-range of each TRP channel, and suggested that these changes in body temperature were mediated by each TRP channel.
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Report
(4 results)
Research Products
(9 results)