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Mechanisms of changes in body temperature induced by intake of food components via thermo TRP channels

Research Project

Project/Area Number 26850086
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Food science
Research InstitutionThe University of Shiga Prefecture

Principal Investigator

Mori Noriyuki  滋賀県立大学, 人間文化学部, 助教 (90585184)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsTRPチャネル / 体温調節 / 食品成分 / マウス / 熱産生 / 食品 / アンタゴニスト
Outline of Final Research Achievements

In this study, to elucidate the mechanisms of changes in body temperature induced by food intake, we focused on thermo TRP channels that have been indicated to have physiological roles in a perception of temperature and examined changes in body temperatures induced by food components activating these channels with mice. We found that the intake of food components which activate TRPV1, TRPM8, and TRPA1, respectively, changed body temperatures with the activation-temperature-range of each TRP channel, and suggested that these changes in body temperature were mediated by each TRP channel.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2017 2016 2015 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (6 results) Remarks (1 results)

  • [Journal Article] Vagus nerve is involved in the changes in body temperature induced by intragastric administration of 1,8-cineole via TRPM8 in mice.2017

    • Author(s)
      Tomomi Urata, Noriyuki Mori, Tsutomu Fukuwatari
    • Journal Title

      Neuroscience Letters

      Volume: 650 Pages: 65-71

    • DOI

      10.1016/j.neulet.2017.04.018

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thermal conditions influence changes in body temperature induced by intragastric administration of capsaicin in mice2016

    • Author(s)
      Noriyuki Mori, Tomomi Urata and Tsutomu Fukuwatari
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 80 Issue: 8 Pages: 1615-1622

    • DOI

      10.1080/09168451.2016.1171700

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] 食品由来TRPM8アゴニスト胃内投与による体温変化の作用機序の検討2017

    • Author(s)
      森 紀之、浦田 朋実、福渡 努
    • Organizer
      日本農芸化学会2017年度大会
    • Place of Presentation
      京都
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] 香辛料由来TRPチャネルアゴニスト摂取による体温変化の作用部位の検討2016

    • Author(s)
      浦田 朋実,森 紀之,福渡 努
    • Organizer
      第31回 日本香辛料研究会
    • Place of Presentation
      長浜
    • Year and Date
      2016-10-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] 環境温度条件がマウスにおけるカプサイシン摂取による体温変化に与える影響2016

    • Author(s)
      森 紀之、浦田 朋実、福渡 努
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 食品成分由来TRPA1アゴニスト摂取による体温変化の作用機序の検討2016

    • Author(s)
      浦田朋実 森紀之 福渡努
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 香辛料由来TRPチャネルアゴニスト摂取による体温変化へのTRPチャネルの関与2015

    • Author(s)
      浦田朋実 森紀之 福渡努
    • Organizer
      第30回 日本香辛料研究会
    • Place of Presentation
      京都
    • Year and Date
      2015-12-11
    • Related Report
      2015 Research-status Report
  • [Presentation] 食品成分摂取によるTRPチャネルを介した体温調節2015

    • Author(s)
      森紀之 浦田朋実 福渡努
    • Organizer
      日本農芸化学会2015年度大会
    • Place of Presentation
      岡山
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Research-status Report
  • [Remarks] 知のリソース

    • URL

      http://db.spins.usp.ac.jp/html/100000125_ja.html

    • Related Report
      2016 Annual Research Report

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Published: 2014-04-04   Modified: 2018-03-22  

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