Elucidation of biologically active laminarin-structure and development of its enzymatic evaluation method
| Project/Area Number |
26850129
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Aquatic life science
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| Research Institution | Hokkaido University |
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Principal Investigator |
Kumagai Yuya 北海道大学, (連合)農学研究科(研究院), 研究員 (00589997)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | ラミナリナーゼ / オリゴ糖 / ラミナリン / 糖質結合モジュール / 糖質加水分解酵素 / GH64 / ラミナリオリゴ糖 |
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| Outline of Final Research Achievements |
Laminarin has biologically active saccharides such as the immunostimulation and antitumor activiy. The laminarin structure differes from spicies, indicating that the relationship of the structures and the expression mechanism of bioactivities is still unclear. In this study, we employed glucanase with a limited hydrolysis activity toward laminarin and attempted for oligosaccharide production. The enzyme produced biologically active oligosaccharides and revealed the hydrolysis pattern of biologically active laminarin.
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Report
(3 results)
Research Products
(10 results)
