| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Although The expression of Cat-1 mRNA increased in skeletal muscle of pigs fed low protein diet increased, but the expression of Cat-2 mRNA did not change. The expression of Cat-1 mRNA did not change, but the expression of Cat-2 mRNA increased in skeletal muscle of pigs restricted diet. The results of C2C12 experiment suggest that the deficiency of amino acid directly induce the expression of Cat-1 mRNA. Moreover, the results of C2C12 experiment suggest that the increase of Cat-2 expression by restrictive diet was not induced directly by energy restriction, but by low concentration of IGF-1 of serum.
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