Searching analysis for fatty acids stimulate ghrelin secretion in lactating dairy cows
Project/Area Number |
26850171
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Animal production science
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Research Institution | Utsunomiya University |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | グレリン / グルカゴン様ペプチド-1 / 消化管ホルモン / 反芻家畜 / 脂肪酸 / 脂質代謝 / インスリン / 成長ホルモン |
Outline of Final Research Achievements |
Ghrelin, a growth hormone secretagogue, may enhance milk production in lactating cows. We have investigated which nutrients could affect ghrelin secretion, then we found that some fatty acids in the diets increase plasma ghrelin concentraion in cows. However, which fatty acid can stimulate ghrelin secretion had not been cleared. In the present study, we examined the effects of feeding some fatty acids on plasma ghrein concentration and we found that ghrelin secretion is stimulated by medium-chain fatty acids, such as C8:0. In another examination, we investigated the effect of duodenal infusion of individual fatty acids on ghrein secretion, but there was not response to any fatty acids.
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Report
(3 results)
Research Products
(6 results)
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[Journal Article] Effects of fat-enriched diet and methionine on insulin sensitivity in lactating cows2015
Author(s)
Fukumori R., Sugino T., Shingu H., Moriya N., Kobayashi H., Yamaji K., El-Sabagh M., Obitsu T., Nagao Y., Taniguchi K., Kushibiki S
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Journal Title
Journal of Animal Science
Volume: 93
Pages: 2778-2784
Related Report
Peer Reviewed
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[Journal Article] Methionine altered insulin sensitivity in lactating cows fed fat-enriched diets2015
Author(s)
R Fukumori, T. Sugino, H. Shingu, N. Moriya, H. Kobayashi, K. Yamaji, M. El-Sabagh, Y. Hasegawa, M. Kojima, K. Kangawa, T. Obitsu, Y. Nagao, K. Taniguchi, and S. Kushibiki
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Journal Title
Journal of Animal Science
Volume: accepted
Related Report
Peer Reviewed
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[Presentation] Effect of duodenal infusion of medium-chain fatty acids on plasma ghrelin concentration in sheep2016
Author(s)
Fukumori R., Takeuchi A., Yanai R., Sarentonglaga B., Ogata K., Yamaguchi M., Hara A., Sato A., Masuda Y, Hasegawa Y., Kojima M., Kangawa K., Sugino T., Nagao Y.
Organizer
17th AAAP congress
Place of Presentation
Fukuoka (Japan)
Year and Date
2016-08-22
Related Report
Int'l Joint Research
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[Presentation] Effects of rumen-protected methionine on lipoprotein properties and the response to insulin in lactating cows fed calcium salts of long-chain fatty acids.2014
Author(s)
Fukumori, R., Hinokidani, M., Sugino, T., Shigu, H., Moriya, N., Kobayashi, H., Yamaji, K., Obitsu, T., Nagao, Y., Taniguchi, K., and Kushibiki, S.
Organizer
International Symposium on the Nutrition of Herbivores/International Symposium on Ruminant Physiology
Place of Presentation
Australia
Year and Date
2014-09-08 – 2014-09-12
Related Report