• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Endocrine mechanism of estrus and ovulation failure in dairy cows and developemnt of new treatment method by using NK3 receptor agonist

Research Project

Project/Area Number 26850195
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

Endo Natsumi  東京農工大学, (連合)農学研究科(研究院), 助教 (40726684)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords乳牛 / 発情 / 排卵障害 / ニューロキニン3受容体 / NKB / ヤギ / 発情行動 / ビデオトラッキング / 発情・排卵障害 / シバヤギ / ニューロキニン3受容体
Outline of Final Research Achievements

High incidence of estrus and ovulation failure in dairy cows has been a worldwide problem in recent years. Firstly, the expression of estrus behavior in lactating dairy cows were investigated by accelerometer system and visual observation. Estrous behavior was detected for 50.0% cycles by visual observation. The accelerometer system detected estrus correctly for 84.6% cycles, which was higher than that by visual observation (P < 0.05). It was suggested that the estrus detection system by the accelerometer system can be utilized as an aid for estrus detection by visual observation. Furthermore, to develop the new therapeutic method to treat anestrus and anovulation animals, the effect of senktide on hormonal secretion and ovarian follicles were determined in follicular-phase goats. The results showed that intravenous administration of senktide stimulates luteinizing hormone secretion, which can enhance the time of ovulation in follicular-phase goats.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2016 2015 2014

All Journal Article (4 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 3 results,  Open Access: 2 results) Presentation (5 results)

  • [Journal Article] Video tracking analysis of behavioral patterns during estrus in goats2016

    • Author(s)
      N. Endo, L. P. Rahayu, T. Arakawa, T. Tanaka
    • Journal Title

      Journal of Reproduction and Development

      Volume: 62 Issue: 1 Pages: 115-119

    • DOI

      10.1262/jrd.2015-118

    • NAID

      130005126313

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effect of intermittent administration of neurokinin 3 receptor agonist on luteinizing hormone secretion, estrus, and ovulation in feed-restricted goats2015

    • Author(s)
      N. Endo, T. Tanaka
    • Journal Title

      Small Ruminant Research

      Volume: 127 Pages: 50-57

    • DOI

      10.1016/j.smallrumres.2015.04.011

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Ovarian and hormonal responses to single or continuous peripheral administration of senktide, a neurokinin 3 receptor agonist, during the follicular phase in goats2015

    • Author(s)
      N. Endo, L. P. Rahayu, Y. Ito, T. Tanaka
    • Journal Title

      Domestic Animal Endocrinology

      Volume: 53 Pages: 136-143

    • DOI

      10.1016/j.domaniend.2015.07.003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effect of senktide, a neurokinin 3 receptor agonist on luteinizing hormone secretion and follicular development in anestrous Shiba goats: a pilot study2014

    • Author(s)
      N. Endo, T. Tanaka
    • Journal Title

      BMC Research Notes

      Volume: 7 Issue: 1 Pages: 773-773

    • DOI

      10.1186/1756-0500-7-773

    • Related Report
      2014 Research-status Report
    • Open Access
  • [Presentation] Ovarian and hormonal responses to single injection or continuous infusion of senktide, a neurokinin 3 receptor agonist, during the follicular phase in goats2015

    • Author(s)
      N. Endo, L. P. Rahayu, Y. Ito, T. Tanaka
    • Organizer
      8th ICFAE
    • Place of Presentation
      ビルン(デンマーク)
    • Year and Date
      2015-08-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] ヤギの動画トラッキングデータに基づく発情行動の解析2015

    • Author(s)
      遠藤 なつ美, 荒川俊也, 田中知己
    • Organizer
      日本畜産学会第119回大会
    • Place of Presentation
      宇都宮
    • Year and Date
      2015-03-27 – 2015-03-29
    • Related Report
      2014 Research-status Report
  • [Presentation] 隠れマルコフモデルを用いたヤギの行動自動推定の試み2015

    • Author(s)
      荒川 俊也, 遠藤 なつ美, 田中 知己
    • Organizer
      研究集会「最適化:モデリングとアルゴリズム28」
    • Place of Presentation
      立川
    • Year and Date
      2015-03-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Ovarian and hormonal responses of female goats to feed restriction and intermittent administration of neurokinin B analog2014

    • Author(s)
      N. Endo, T. Tanaka.
    • Organizer
      World Congress of Reproductive Biology 2014
    • Place of Presentation
      エディンバラ(スコットランド)
    • Year and Date
      2014-09-02 – 2014-09-04
    • Related Report
      2014 Research-status Report
  • [Presentation] 制限給餌下のヤギにおけるニューロキニンB類縁物質の投与が黄体形成ホルモン分泌, 卵胞発育および発情に及ぼす影響2014

    • Author(s)
      遠藤 なつ美, 田中 知己
    • Organizer
      第107回日本繁殖生物学会
    • Place of Presentation
      帯広
    • Year and Date
      2014-08-21 – 2014-08-23
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi