| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Amino acid infusion in dogs inhibited insulin secretion reduced the effect which attenuates the decrease in body temperature during anesthesia. Therefore, in healthy dogs, amino acid infusion can attenuates the decrease in body temperature during anesthesia by facilitating insulin secretion. In skeletal muscle and liver derived from dogs infused amino acids, Akt-mTOR pathway was activated. In addition, Akt-mTOR pathway in skeletal muscle can be activated without insulin.
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