Visualization and functional analysis of sex pheromone neural circuit of insects using an activity-dependent gene expression
| Project/Area Number |
26850218
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Insect science
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| Research Institution | Kanazawa University |
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Principal Investigator |
Taketoshi Kiya 金沢大学, 自然システム学系, 准教授 (90532309)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 初期応答遺伝子 / 神経活動 / フェロモン / 昆虫 / カイコ / ショウジョウバエ / 脳 / Hr38 / 性行動 / fruitless |
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| Outline of Final Research Achievements |
How do animals select their behavior in response to certain sensory inputs? Appropriate response to sensory information is critical for animal survival. In the present study, I focused on the brain of insects which has low complexity, but has similar circuit property and molecular basis as the brain of other animals including vertebrates. In many insects, sex pheromone induces stereotypic courtship behavior with clear relationship between receptor and behavior. Here, I established a novel neural circuit tracing method utilizing an activity-dependent gene expression. Recently, I identified a novel immediate early gene Hr38, whose expression increases in response to neural activity. In the present study, I used the promoter activity of Hr38 to express GFP in order to visualize neurons activated by sex pheromone or courtship behavior. In addition to previously known neural circuits, I identified novel circuits involved in courtship behavior.
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Report
(3 results)
Research Products
(17 results)
