Investigation for novel ommochrome pigmentation genes based on silkworm egg and eye color mutants
| Project/Area Number |
26850220
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Insect science
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| Research Institution | Ibaraki University (2015-2017)
National Institute of Agrobiological Sciences (2014) |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 昆虫 / 色素 / オモクローム / カイコ |
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| Outline of Final Research Achievements |
Ommochromes are major group of insect pigments which contribute to red, purple, brown body coloration and also known as screening pigments of ommatidia. However, molecular mechanisms of the synthesis of these pigments have not been fully understood. We found that Bombyx mori cardinal gene encoding a haem peroxidase was responsible for the pink-eyed white egg mutation, pe. Eggs and eyes of pe mutant have a very small amount of pigments, due to defect in converting the precursor 3-hydroxykynurenine into various ommochrome pigments, suggesting the function of cardinal as a key synthesis enzyme for multiple ommochrome pigments. We also conducted linkage analyses for three egg color mutants; brown egg 2 (b-2), brown egg 4 (b-4), and maternal brown of tsujita (b-t) by ddRADseq, and found novel characteristics for b-4 and b-t mutants.
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Report
(5 results)
Research Products
(9 results)
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[Journal Article] Positional cloning of a Bombyx pink eyed white egg locus reveals the major role of cardinal in ommochrome synthesis2016
Author(s)
Osanai-Futahashi M, Tatematsu KI, Futahashi R, Narukawa J, Takasu Y, Kayukawa T, Shinoda T, Ishige T, Yajima S, Tamura T, Yamamoto K, Sezutsu H
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Journal Title
Heredity
Volume: 116(2)
Issue: 2
Pages: 135-145
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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