| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Ommochromes are major group of insect pigments which contribute to red, purple, brown body coloration and also known as screening pigments of ommatidia. However, molecular mechanisms of the synthesis of these pigments have not been fully understood. We found that Bombyx mori cardinal gene encoding a haem peroxidase was responsible for the pink-eyed white egg mutation, pe. Eggs and eyes of pe mutant have a very small amount of pigments, due to defect in converting the precursor 3-hydroxykynurenine into various ommochrome pigments, suggesting the function of cardinal as a key synthesis enzyme for multiple ommochrome pigments. We also conducted linkage analyses for three egg color mutants; brown egg 2 (b-2), brown egg 4 (b-4), and maternal brown of tsujita (b-t) by ddRADseq, and found novel characteristics for b-4 and b-t mutants.
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