| Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
In this study, we analyzed some rotaviruses-glycans interaction, and revealed that rotavirus binding glycans are different depending on the type of virus strain. We also analyzed N-glycans expressed on rotavirus particles, and found that glycan profiles of rotavirus is more complicated than the one reported in the past. These studies suggested that analysis of virus binding glycans and virus expressing glycans is useful for identifying rotavirus strain. In addition, we developed a device that can analyze virus binding glycans and virus expressing glycans simultaneously. I hope that this device will be applied to rotavirus surveillance.
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