Development of chronic muscle pain model and understanding of pathological condition by using optogenetics
| Project/Area Number |
26860158
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Environmental physiology(including physical medicine and nutritional physiology)
|
|---|
| Research Institution | Nagoya University |
|---|
Principal Investigator |
HAYASHI KOEI 名古屋大学, 環境医学研究所, 研究員 (00579592)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
|---|
| Keywords | 慢性筋痛症 / 光遺伝学 / 筋硬結 / チャネルロドプシン2 / 筋筋膜性疼痛症候群 / トリガーポイント / チャネルロドプシン |
|---|
| Outline of Final Research Achievements |
We tried to develop a chronic muscle pain model with taut band and understand a pathological condition by using optogenetics. Light-stimulation of skeletal muscle expressing the light-sensitive channel Channelrhodopsin-2 (ChR2) evoked tetanic contractions. Light-stimulation exposed directly to the muscle evoked larger tetanic contractions compare with exposed through the skin.
|
Report
(3 results)
Research Products
(10 results)
