Prediction of HCC reccurrence by proteome analyses

• Project/Area Number: 26860211
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pathological medical chemistry
• Research Institution: Kobe University
• Principal Investigator: Masaya Saito 神戸大学, 医学部附属病院, 医員 (00631558)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 肝細胞癌

Outline of Final Research Achievements

The factor associated with the reccurrence of hepatocellular carcinoma (HCC) was found between early reccurrence group and late reccurrence group.

Research Products

• [Journal Article] The serum level of NX-DCP-R, but not DCP, is not increased in alcoholic liver disease without hepatocellular carcinoma. (2016)
  • Author(s): Saito M, Yano Y, Hirano H, Momose K, Mouri K, Hishimoto A, Yoshida M, Azuma T.
  • Journal Title: Cancer Biomark. Volume: 16 Issue: 1 Pages: 171-180
  • DOI: 10.3233/cbm-150553
  • Peer Reviewed
• [Journal Article] Serum level of taurine would be associated with the amelioration of minimal hepatic encephalopathy in cirrhotic patients. (2016)
  • Author(s): Masaya Saito, Hirotaka Hirano, Yoshihiko Yano, Kenji Momose, Masaru Yoshida, Takeshi Azuma.
  • Journal Title: Hepatol Res Volume: 46 Issue: 2 Pages: 215-224
  • DOI: 10.1111/hepr.12565
  • Peer Reviewed
• [Journal Article] Visceral fat accumulation is associated with increased mortality rate after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma. (2015)
  • Author(s): Masaya Saito, Yoshihiko Yano, Hirotaka Hirano, Kenji Momose, Yuki Kawano, Masaru Yoshida, Takeshi Azuma.
  • Journal Title: J Cancer Ther Volume: 6 Issue: 13 Pages: 1124-1136
  • DOI: 10.4236/jct.2015.613122
  • Peer Reviewed
• [Journal Article] Recent topics of diagnosis and treatment in minimal hepatic encephalopathy of cirrhotic patients. (2015)
  • Author(s): Masaya Saito, Hirotaka Hirano, Yoshihiko Yano, Hiroki Hayashi, Kenji Momose, Akihiro Minami, Yuki Kawano, Masaru Yoshida, Takeshi Azuma.
  • Journal Title: Journal of Hepatitis Volume: 1 Pages: 2-2
  • Peer Reviewed
• [Journal Article] Identification of Lipid Species Linked to the Progression of Non-alcoholic Fatty Liver Disease. (2015)
  • Author(s): Yuki Kawano, Shin Nishiumi, Masaya Saito, Yoshihiko Yano, Takeshi Azuma, Masaru Yoshida.
  • Journal Title: Curr Drug Targets Volume: 16 Pages: 1293-1330
  • Peer Reviewed
• [Journal Article] Serum NX-DCP is a new noninvasive model for predicting significant liver fibrosis in chronic hepatitis C. (2015)
  • Author(s): Masaya Saito, Yoshihiko Yano, Hirotaka Hirano, Kenji Momose, Masaru Yoshida, Takeshi Azuma.
  • Journal Title: Hepat Mon Volume: 15 Issue: 2
  • DOI: 10.5812/hepatmon.22978
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Branched-chain amino acid granules improve non-protein respiratory quotient after radiofrequency ablation. (2014)
  • Author(s): Masaya Saito, Yoshihiko Yano, Akihiro Minami, Hirotaka Hirano, Kenji Momose, Maki Sugimoto, Masaru Yoshida, Takeshi Azuma.
  • Journal Title: Intern Med Volume: 53 Pages: 1469-1475
  • NAID: 130004466403
  • Peer Reviewed / Open Access / Acknowledgement Compliant